[HTML][HTML] Trypanocidal and Anti-Inflammatory Effects of Three ent-Kaurane Diterpenoids from Gymnocoronis spilanthoides var. subcordata (Asteraceae)
MG Selener, J Borgo, MB Sarratea, MA Delfino… - Pharmaceutics, 2024 - mdpi.com
Chagas disease, caused by the protozoan Trypanosoma cruzi, affects 6–7 million people
worldwide. The dichloromethane extract obtained from the aerial parts of Gymnocoronis …
worldwide. The dichloromethane extract obtained from the aerial parts of Gymnocoronis …
[HTML][HTML] Trypanocidal activity of four sesquiterpene lactones isolated from Asteraceae species
OG Elso, AE Bivona, A Sanchez Alberti, N Cerny… - Molecules, 2020 - mdpi.com
The sesquiterpene lactones eupatoriopicrin, estafietin, eupahakonenin B and minimolide
have been isolated from Argentinean Astearaceae species and have been found to be …
have been isolated from Argentinean Astearaceae species and have been found to be …
[HTML][HTML] In Vivo Anti-Trypanosoma cruzi Activity of Hydro-Ethanolic Extract and Isolated Active Principles from Aristeguietia glutinosa and Mechanism of Action …
J Varela, E Serna, S Torres, G Yaluff, NIV De Bilbao… - Molecules, 2014 - mdpi.com
The currently available treatments for Chagas disease show limited therapeutic potential
and are associated with serious side effects. Attempting to find alternative drugs isolated …
and are associated with serious side effects. Attempting to find alternative drugs isolated …
Trypanosomicidal kaurane diterpenes from Wedelia paludosa
Abstract The diterpenes ent-kaur-16-en-19-oic acid, ent-kaur-9 (11), 16 (17)-dien-19-oic
acid and 3α-angeloiloxy-ent-kaur-16-en-19-oic acid were identified as trypanosomicidal …
acid and 3α-angeloiloxy-ent-kaur-16-en-19-oic acid were identified as trypanosomicidal …
Anti-Trypanosoma cruzi activity in vitro of phases and isolated compounds from Excoecaria lucida leaves
CF da Silva, AO Pacheco, RN Alves… - Medicinal …, 2018 - ingentaconnect.com
Background: Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. This
illness is found mainly in 21 Latin American countries and an estimated 8 million people are …
illness is found mainly in 21 Latin American countries and an estimated 8 million people are …
[HTML][HTML] Amaryllidaceae alkaloids with anti-Trypanosoma cruzi activity
N Martinez-Peinado, N Cortes-Serra… - Parasites & vectors, 2020 - Springer
Background Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected
disease that affects~ 7 million people worldwide. Development of new drugs to treat the …
disease that affects~ 7 million people worldwide. Development of new drugs to treat the …
[PDF][PDF] Anti-Trypanosoma cruzi Activity in vitro of Phases and Isolated Com-pounds from Excoecaria lucida Leaves
CF da Silva, AO Pacheco, RN Alves… - Medicinal Chemistry, 2018 - academia.edu
Background: Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. This
illness is found mainly in 21 Latin American countries and an estimated 8 million people are …
illness is found mainly in 21 Latin American countries and an estimated 8 million people are …
Dibenzylbutane neolignans from Saururus cernuus L.(Saururaceae) displayed anti-Trypanosoma cruzi activity via alterations in the mitochondrial membrane potential
JR Brito, TA Da Costa-Silva, AG Tempone, EA Ferreira… - Fitoterapia, 2019 - Elsevier
The MeOH extract from leaves of Saururus cernuus L.(Saururaceae) displayed in vitro
activity against trypomastigote forms of T. cruzi (100% of parasite death at 200 μg/mL) …
activity against trypomastigote forms of T. cruzi (100% of parasite death at 200 μg/mL) …
Grandiflorenic acid isolated from Sphagneticola trilobata against Trypanosoma cruzi: Toxicity, mechanisms of action and immunomodulation
MD Gonçalves, BT da Silva Bortoleti… - Toxicology in Vitro, 2022 - Elsevier
Grandiflorenic acid (GFA) is one of the main kaurane diterpenes found in different parts of
Sphagneticola trilobata. It has several biological activities, especially antiprotozoal action. In …
Sphagneticola trilobata. It has several biological activities, especially antiprotozoal action. In …
[HTML][HTML] Antitrypanosomal activity of a semi-purified subfraction rich in labdane sesquiterpenes, obtained from flowers of Anthemis tinctoria, against Trypanosoma cruzi
NLR Bittencourt, T Ueda-Nakamura… - Pharmacology & …, 2011 - scirp.org
In Brazil and several other Latin American countries, Chagas' disease still constitutes a
serious medical and social problem, and there is a need to develop new, more-potent drugs …
serious medical and social problem, and there is a need to develop new, more-potent drugs …