Most of the present anticancer drugs are highly cytotoxic and focus mainly on killing tumor
cells rather than slowing the progress of cancer metastasis. Evidence has been reported that …

Here we showed that ursolic acid (UA), a pentacyclic triterpene natural product, and its novel
prodrug derivative US597 suppressed cancer cells adhesion, invasion and migration. This …

Background: Metastasis is often derived from increased invasion and migration of tumor
cells, and is the most frequent cause of cancer-associated death. Either the prophylactic or …

Rhazya stricta is a medicinal plant that is widely used in Saudi folklore medicine for
treatment of various diseases. R. stricta fruit powder was sequentially extracted with n …

Recently, we reported that Rhus coriaria exhibits anticancer activities by promoting cell cycle
arrest and autophagic cell death of the metastatic triple negative MDA-MB-231 breast cancer …

Background We have recently reported that Origanum majorana exhibits anticancer activity
by promoting cell cycle arrest and apoptosis of the metastatic MDA-MB-231 breast cancer …

Metastasis is one of the most important factors related to breast cancer therapeutic efficacy.
Ursolic acid, a naturally occurring triterpenoid, has various anticancer activities. In this study …

Metastasis is the main cause of cancer-related death. Despite its high fatality, a
comprehensive study that covers anti-metastasis of herbal medicines has not yet been …

A112 Conventional chemotherapy is commonly used in the treatment of metastasis cancers
although it exhibits cytotoxic effects on normal cells. Agents that target metastatic …

Cancer metastasis, involving multiple processes and various cytophysiological changes, is a
primary cause of cancer death and may complicate clinical management, even leading to …