[HTML][HTML] The role of different immunocompetent cell populations in the pathogenesis of head and neck cancer—regulatory mechanisms of pro-and anti-cancer activity …

K Starska-Kowarska - Cancers, 2023 - mdpi.com
Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …

[HTML][HTML] The emerging role of immunotherapy in head and neck squamous cell carcinoma (HNSCC): anti-tumor immunity and clinical applications

P Economopoulou, C Perisanidis… - Annals of …, 2016 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinoma (HNSCC) carries a poor prognosis, with low
survival rates for advanced stage tumors and minimal improvement in survival trends …

Immunology and immunotherapy of head and neck cancer

RL Ferris - Journal of clinical oncology, 2015 - ascopubs.org
The immune system plays a key role in the development, establishment, and progression of
head and neck squamous cell carcinoma (HNSCC). A greater understanding of the …

[HTML][HTML] The role of T-cells in head and neck squamous cell carcinoma: from immunity to immunotherapy

MPS Damasio, CS Nascimento, LM Andrade… - Frontiers in …, 2022 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) encompass a group of complex entities
of tumours affecting the aerodigestive upper tract. The main risk factors are strongly related …

[HTML][HTML] Immunological network in head and neck squamous cell carcinoma—a prognostic tool beyond HPV status

A Fialová, V Koucký, M Hajdušková, K Hladíková… - Frontiers in …, 2020 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous disease that
affects more than 800,000 patients worldwide each year. The variability of HNSCC is …

Immune alterations and immunotherapy prospects in head and neck cancer

V Varilla, J Atienza, CA Dasanu - Expert opinion on biological …, 2013 - Taylor & Francis
Introduction: Several literature sources have suggested that subjects with head and neck
squamous cell carcinoma (HNSCC) display significant abnormalities of immunocompetent …

Innovative perspectives of immunotherapy in head and neck cancer. From relevant scientific rationale to effective clinical practice

Y Lalami, A Awada - Cancer treatment reviews, 2016 - Elsevier
It is now well established that head and neck cancer carcinogenesis is characterized by
genetic instability and several immune defects, leading to unique host–tumor interactions. In …

[HTML][HTML] Targeting the immune microenvironment in the treatment of head and neck squamous cell carcinoma

HC Wang, LP Chan, SF Cho - Frontiers in Oncology, 2019 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive solid tumor, with
a 5-year mortality rate of~ 50%. The development of immunotherapies has improved the …

[HTML][HTML] Current status and perspective of tumor immunotherapy for head and neck squamous cell carcinoma

C Yu, Q Li, Y Zhang, ZF Wen, H Dong… - Frontiers in Cell and …, 2022 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) have a high incidence and mortality
rate, and investigating the pathogenesis and potential therapeutic strategies of HNSCC is …

[HTML][HTML] A review on the advances and challenges of immunotherapy for head and neck cancer

G Cheng, H Dong, C Yang, Y Liu, Y Wu, L Zhu… - Cancer Cell …, 2021 - Springer
Head and neck cancer (HNC), which includes lip and oral cavity, larynx, nasopharynx,
oropharynx, and hypopharynx malignancies, is one of the most common cancers worldwide …