[HTML][HTML] Biological basis for novel mesothelioma therapies

J Obacz, H Yung, M Shamseddin, E Linnane… - British Journal of …, 2021 - nature.com
Mesothelioma is an aggressive cancer that is associated with exposure to asbestos.
Although asbestos is banned in several countries, including the UK, an epidemic of …

Novel insights into mesothelioma biology and implications for therapy

TA Yap, JG Aerts, S Popat, DA Fennell - Nature Reviews Cancer, 2017 - nature.com
Malignant mesothelioma is a universally lethal cancer that is increasing in incidence
worldwide. There is a dearth of effective therapies, with only one treatment (pemetrexed and …

Biological agents involved in malignant mesothelioma: relevance as biomarkers or therapeutic targets

S Crispi, I Cardillo, EP Spugnini, G Citro… - Current Cancer Drug …, 2010 - ingentaconnect.com
Malignant mesothelioma (MM) is a rare, highly aggressive tumor that arises from the surface
serosal cells (pleural, peritoneal and pericardial cavities). Epidemiological and clinical data …

[HTML][HTML] Tumor immune microenvironment and genetic alterations in mesothelioma

S Hiltbrunner, L Mannarino, MB Kirschner… - Frontiers in …, 2021 - frontiersin.org
Malignant pleural mesothelioma (MPM) is a rare and fatal disease of the pleural lining. Up to
80% of the MPM cases are linked to asbestos exposure. Even though its use has been …

Latest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapies

A Bononi, A Napolitano, HI Pass, H Yang… - Expert review of …, 2015 - Taylor & Francis
Malignant mesothelioma is an aggressive cancer whose pathogenesis is causally linked to
occupational exposure to asbestos. Familial clusters of mesotheliomas have been observed …

Translating mesothelioma molecular genomics and dependencies into precision oncology-based therapies

TK Hinz, LE Heasley - Seminars in Cancer Biology, 2020 - Elsevier
Malignant pleural mesothelioma (MPM) is a rare, yet lethal asbestos-induced cancer and
despite marked efforts to reduce occupational exposure, the incidence has not yet …

[HTML][HTML] Novel and future treatment options in mesothelioma: a systematic review

D Štrbac, V Dolžan - International journal of molecular sciences, 2022 - mdpi.com
Mesothelioma is a rare tumor, frequently associated with asbestos exposure, arising from
pleura and peritoneum. Traditionally, diagnosis and treatment have been difficult in a clinical …

Malignant mesothelioma: development to therapy

JK Thompson, CM Westbom… - Journal of cellular …, 2014 - Wiley Online Library
Malignant mesothelioma (MM) is an aggressive cancer of the mesothelium caused by
asbestos. Asbestos use has been reduced but not completely stopped. In addition, natural or …

Immunotherapy advances for mesothelioma treatment

E Bakker, A Guazzelli, F Ashtiani… - Expert review of …, 2017 - Taylor & Francis
Introduction: Mesothelioma is a rare type of cancer that is strongly tied to asbestos exposure.
Despite application of different modalities such as chemotherapy, radiotherapy and surgery …

Biological and immunological aspects of malignant mesothelioma

MJ Garlepp, CC Leong - European Respiratory Journal, 1995 - Eur Respiratory Soc
Malignant mesothelioma (MM) is an aggressive tumour, which is strongly associated with
previous asbestos exposure and is resistant to all conventional anticancer therapies. An …