Polyamines and gut microbiota

R Tofalo, S Cocchi, G Suzzi - Frontiers in nutrition, 2019 - frontiersin.org
The microbiota of gut is the community of microbes living in an individual's gastrointestinal
tract. Several bacterial genera and species act in a concerted manner to establish metabolic …

Polyamine metabolism and transport in gut microbes

S Kurihara - Bioscience, biotechnology, and biochemistry, 2022 - academic.oup.com
Polyamines (putrescine, spermidine, and spermine) are compounds with amino groups at
both ends of a hydrocarbon. Polyamines produced by intestinal bacteria suppress chronic …

Dietary and gut microbiota polyamines in obesity-and age-related diseases

B Ramos-Molina, MI Queipo-Ortuño… - Frontiers in …, 2019 - frontiersin.org
The polyamines putrescine, spermidine, and spermine are widely distributed polycationic
compounds essential for cellular functions. Intracellular polyamine pools are tightly …

Bioactive polyamine production by a novel hybrid system comprising multiple indigenous gut bacterial strategies

Y Kitada, K Muramatsu, H Toju, R Kibe, Y Benno… - Science …, 2018 - science.org
Metabolites of the intestinal microbiota are thought to be generated through metabolic
pathways spanning multiple taxa of intestinal bacteria. We have previously shown that the …

Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon

A Nakamura, S Kurihara, D Takahashi… - Nature …, 2021 - nature.com
Intestinal microbiota-derived metabolites have biological importance for the host.
Polyamines, such as putrescine and spermidine, are produced by the intestinal microbiota …

Postbiotics: Metabolites and mechanisms involved in microbiota-host interactions

MCG Peluzio, JA Martinez, FI Milagro - Trends in Food Science & …, 2021 - Elsevier
Background The knowledge on the mechanisms through which the metabolites produced by
the gut microbiota (postbiotics) prevent diseases, induce therapeutic responses, and behave …

The relationship between microbiota and polyamine concentration in the human intestine: a pilot study

M Matsumoto, Y Benno - Microbiology and immunology, 2007 - Wiley Online Library
The fecal microbiota of 10 hospitalized elderly subjects and 14 healthy adults were analyzed
by terminal‐restriction fragment length polymorphism (T‐RFLP) analysis using HhaI, MspI …

The molecular and physiological effects of protein-derived polyamines in the intestine

AF Bekebrede, J Keijer, WJJ Gerrits, VCJ Boer - Nutrients, 2020 - mdpi.com
Consumption of a high-protein diet increases protein entry into the colon. Colonic microbiota
can ferment proteins, which results in the production of protein fermentation end-products …

Intestinal luminal putrescine is produced by collective biosynthetic pathways of the commensal microbiome

A Nakamura, T Ooga, M Matsumoto - Gut Microbes, 2019 - Taylor & Francis
The intestinal microbiome produces various metabolites that may harm or benefit the host.
However, the production pathways of these metabolites have not been well characterised …

[引用][C] The gut microbiome in health and disease

C Owyang, GD Wu - Gastroenterology, 2014 - gastrojournal.org
Every May, Gastroenterology publishes a supple-mental thirteenth issue devoted to a topic
of particular interest and importance to both the practice and science of gastroenterology …