Rats choose alcohol over social reward in an operant choice procedure

NJ Marchant, AJ McDonald, R Matsuzaki… - …, 2023 - nature.com
The interaction between social factors and alcohol addiction is complex, with potential for
both positive and negative contributions to drug use and abstinence. Positive social …

Wistar rats choose alcohol over social interaction in a discrete-choice model

G Augier, V Schwabl, A Lguensat, M Atudorei… - …, 2023 - nature.com
Animal models of substance use disorders have been criticized for their limited translation.
One important factor behind seeking and taking that has so far been largely overlooked is …

The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward

M Venniro, LV Panlilio, DH Epstein… - …, 2021 - nature.com
Social reinforcement-based treatments are effective for many, but not all, people with
addictions to drugs. We recently developed an operant rat model that mimics features of one …

Operant social reward decreases incubation of heroin craving in male and female rats

M Venniro, TI Russell, M Zhang, Y Shaham - Biological psychiatry, 2019 - Elsevier
Background We recently reported that operant social choice–induced voluntary abstinence
prevents incubation of methamphetamine craving. Here, we determined whether social …

An operant social self-administration and choice model in rats

M Venniro, Y Shaham - Nature protocols, 2020 - nature.com
It is difficult to translate results from animal research on addiction to an understanding of the
behavior of human drug users. Despite decades of basic research on neurobiological …

Social preference and drug self-administration: a preclinical model of social choice within peer groups

MA Smith, EG Pitts - Drug and alcohol dependence, 2014 - Elsevier
Background selection models of substance use propose that individuals choose or self-
select into peer groups based on shared substance use histories. Few experimental studies …

The two faces of social interaction reward in animal models of drug dependence

R El Rawas, A Saria - Neurochemical research, 2016 - Springer
Drug dependence is a serious health and social problem. Social factors can modify
vulnerability to developing drug dependence, acting as risk factors or protective factors …

The effects of a shared history of drug exposure on social choice

MA Smith, JC Strickland, SE Bills… - Behavioural …, 2015 - journals.lww.com
Selection theories of drug use propose that individuals choose or self-select into peer
groups on the basis of perceived similarities with other group members with regard to their …

Characterization of operant social interaction in rats: effects of access duration, effort, peer familiarity, housing conditions, and choice between social interaction vs …

JJ Chow, NJ Beacher, JM Chabot, M Oke… - …, 2022 - Springer
Rationale and objective Social factors play a critical role in drug addiction. We recently
showed that rats will abstain from methamphetamine, cocaine, heroin, and remifentanil self …

Peer influences on drug self-administration: an econometric analysis in socially housed rats

GW Peitz, JC Strickland, EG Pitts, M Foley… - Behavioural …, 2013 - journals.lww.com
Social-learning theories of substance use propose that members of peer groups influence
the drug use of other members by selectively modeling, reinforcing, and punishing either …