Strategies toward rheumatoid arthritis therapy; the old and the new

M Abbasi, MJ Mousavi, S Jamalzehi… - Journal of cellular …, 2019 - Wiley Online Library
Currently, medications used to treat rheumatoid arthritis (RA) are glucocorticoids (GCs) and
nonsteroidal anti‐inflammatory drugs (NSAIDs), predominantly used for controlling the pain …

[HTML][HTML] Advances in the treatment of rheumatoid arthritis

N Vivar, RF Van Vollenhoven - F1000prime reports, 2014 - ncbi.nlm.nih.gov
The intense pursuit of novel therapies in rheumatoid arthritis has provided physicians with
an assorted set of biologic drugs to treat patients with moderate to severe disease activity …

Rheumatoid arthritis: recent advances on its etiology, role of cytokines and pharmacotherapy

J Alam, I Jantan, SNA Bukhari - Biomedicine & pharmacotherapy, 2017 - Elsevier
An autoimmune disease is defined as a clinical syndrome resulted from an instigation of
both T cell and B cell or individually, in the absence of any present infection or any sort of …

Current therapeutic options in the treatment of rheumatoid arthritis

BM Köhler, J Günther, D Kaudewitz… - Journal of clinical …, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic
inflammation of the joints. Untreated RA leads to a destruction of joints through the erosion …

Management of rheumatoid arthritis: an overview

AF Radu, SG Bungau - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology,
primarily affecting the joints, then extra-articular manifestations can occur. Due to its …

[PDF][PDF] Biological therapies in rheumatic diseases

F Conti, F Ceccarelli, L Massaro, E Cipriano… - Clin Ter, 2013 - seu-roma.it
The development of the biological drugs has revolutionized the therapeutic approach of the
chronic inflammatory rheumatic diseases, particularly in patients resistant to standard …

Biologics in development for rheumatoid arthritis: relevance to osteoarthritis

SB Abramson, Y Yazici - Advanced drug delivery reviews, 2006 - Elsevier
The osteoarthritis disease process affects not only the cartilage but also the entire joint
structure, including the synovium, bone and periarticular muscles. Characteristically …

Recent progress in treatments of rheumatoid arthritis: an overview of developments in biologics and small molecules, and remaining unmet needs

Y Tanaka - Rheumatology, 2021 - academic.oup.com
Through treatment with biological DMARDs (bDMARDs) or targeted synthetic (tsDMARDs)
such as Janus kinase (JAK) inhibitors in addition to MTX, clinical remission has become a …

Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis

YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …

Rheumatoid arthritis: current and future trends

K Chaudhari, S Rizvi, BA Syed - Nat Rev Drug Discov, 2016 - nature.com
Rheumatoid arthritis (RA) is a chronic autoimmune condition of the connective tissue in
synovial joints characterized by inflammation that can lead to impaired movement and …