Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in
pregnancy remains to be established, particularly when coadministered with azithromycin …

To determine the pharmacokinetic disposition of sulfadoxine (SDOX) and pyrimethamine
(PYR) when administered as intermittent presumptive treatment during pregnancy (IPTp) for …

Sulfadoxine/pyrimethamine is recommended for intermittent preventative treatment of
malaria during pregnancy. Data from 98 women during pregnancy and 77 after delivery in …

Malaria during pregnancy is associated with maternal and fetal morbidity and mortality. In
order to minimize the burden, sulfadoxine–pyrimethamine (SP) is widely used in Africa as an …

Despite extensive use and accumulated evidence of safety, there have been few
pharmacokinetic studies from which appropriate chloroquine (CQ) dosing regimens could …

Abstract Background. Sulfadoxine-pyrimethamine (SP) is among the most commonly used
antimalarial drugs during pregnancy, yet the pharmacokinetics of SP are unknown in …

Emerging malaria parasite sulfadoxine-pyrimethamine (SP) resistance has prompted
assessment of alternatives for intermittent preventive treatment in pregnancy (IPTp). The …

Background Sulphadoxine–pyrimethamine (SP) is widely used as an intermittent preventive
treatment for malaria in pregnancy (IPTp). However, pharmacokinetic studies in pregnancy …

Introduction: The first-line therapy for the intermittent preventive treatment of malaria in
pregnancy (IPTp) is sulphadoxine–pyrimethamine (SP). There is an urgent need to identify …

Background. The use of sulfadoxine-pyrimethamine (SP) for intermittent preventive
treatment in pregnancy (IPTp) is threatened by the spread of resistance to SP. Therefore, we …