Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial
M Bafadhel, S McKenna, S Terry, V Mistry… - American journal of …, 2012 - atsjournals.org
Rationale: Exacerbations of chronic obstructive pulmonary disease (COPD) and responses
to treatment are heterogeneous. Objectives: Investigate the usefulness of blood eosinophils …
to treatment are heterogeneous. Objectives: Investigate the usefulness of blood eosinophils …
Blood eosinophils and response to maintenance chronic obstructive pulmonary disease treatment. Data from the FLAME trial
N Roche, KR Chapman, CF Vogelmeier… - American journal of …, 2017 - atsjournals.org
Rationale: Post hoc analyses suggest that blood eosinophils have potential as a predictive
biomarker of inhaled corticosteroid efficacy in the management of chronic obstructive …
biomarker of inhaled corticosteroid efficacy in the management of chronic obstructive …
[HTML][HTML] Blood eosinophil levels as a biomarker in COPD
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disorder and patients
respond differently to treatment. Blood eosinophils are a potential biomarker to stratify …
respond differently to treatment. Blood eosinophils are a potential biomarker to stratify …
Blood eosinophil guided prednisolone therapy for exacerbations of COPD: a further analysis
M Bafadhel, L Davies, PMA Calverley… - European …, 2014 - Eur Respiratory Soc
Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with
significant morbidity and mortality [ 1]. Current guidelines advocate the use of systemic …
significant morbidity and mortality [ 1]. Current guidelines advocate the use of systemic …
Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials
D Singh, JA Wedzicha, S Siddiqui, A de la Hoz… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the …
H Watz, K Tetzlaff, EFM Wouters, A Kirsten… - The lancet Respiratory …, 2016 - thelancet.com
Background Blood eosinophil counts might predict response to inhaled corticosteroids (ICS)
in patients with chronic obstructive pulmonary disease (COPD) and a history of …
in patients with chronic obstructive pulmonary disease (COPD) and a history of …
The reproducibility of COPD blood eosinophil counts
T Southworth, G Beech, P Foden… - European …, 2018 - Eur Respiratory Soc
Post hoc and pre-specified analyses of chronic obstructive pulmonary disease (COPD)
randomised controlled trials have shown that higher blood eosinophil counts predict greater …
randomised controlled trials have shown that higher blood eosinophil counts predict greater …
Blood eosinophils and exacerbations in chronic obstructive pulmonary disease. The Copenhagen General Population Study
S Vedel-Krogh, SF Nielsen, P Lange… - American journal of …, 2016 - atsjournals.org
Rationale: Whether high blood eosinophils are associated with chronic obstructive
pulmonary disease (COPD) exacerbations among individuals with COPD in the general …
pulmonary disease (COPD) exacerbations among individuals with COPD in the general …
Relationship of blood eosinophil count to exacerbations in chronic obstructive pulmonary disease
RS Zeiger, TN Tran, RK Butler, M Schatz, Q Li… - The Journal of Allergy …, 2018 - Elsevier
Background Eosinophilic airway inflammation characterizes a chronic obstructive pulmonary
disease (COPD) phenotype that requires more study. Objective To investigate the …
disease (COPD) phenotype that requires more study. Objective To investigate the …
Blood eosinophils as a marker of response to inhaled corticosteroids in COPD
NC Barnes, R Sharma, S Lettis… - European Respiratory …, 2016 - Eur Respiratory Soc
Identification of a biomarker that predicts response to inhaled corticosteroids (ICS) would
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …
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