Investigating parasites in three dimensions: trends in volume microscopy

C Cooper, RCA Thompson, PL Clode - Trends in parasitology, 2023 - cell.com
To best understand parasite, host, and vector morphologies, host–parasite interactions, and
to develop new drug and vaccine targets, structural data should, ideally, be obtained and …

Microscopy and the helminth parasite

DW Halton - Micron, 2004 - Elsevier
Microscopy has a long and distinguished history in the study of helminth parasites and has
made a singularly outstanding contribution to understanding how these complex animals …

Visualizing the 3D Architecture of Multiple Erythrocytes Infected with Plasmodium at Nanoscale by Focused Ion Beam-Scanning Electron Microscopy

LC Soares Medeiros, W De Souza, C Jiao, H Barrabin… - PLoS …, 2012 - journals.plos.org
Different methods for three-dimensional visualization of biological structures have been
developed and extensively applied by different research groups. In the field of electron …

Three-Dimensional Imaging of Toxoplasma gondii–Host Cell Interactions within the Parasitophorous Vacuole

H Schatten, H Ris - Microscopy and Microanalysis, 2004 - academic.oup.com
The protozoan parasite Toxoplasma gondii is a representative of apicomplexan parasites
that invades host cells through an unconventional motility mechanism. During host cell …

Viral infection at high magnification: 3D electron microscopy methods to analyze the architecture of infected cells

I Romero-Brey, R Bartenschlager - Viruses, 2015 - mdpi.com
As obligate intracellular parasites, viruses need to hijack their cellular hosts and reprogram
their machineries in order to replicate their genomes and produce new virions. For the direct …

Imaging as a (pre) clinical tool in parasitology

CM de Korne, L van Lieshout, FWB van Leeuwen… - Trends in …, 2023 - cell.com
Imaging of parasites is central to diagnosis of many parasitic diseases and has thus far
played an important role in the development of antiparasitic strategies. The development of …

An introduction to scanning transmission electron microscopy for the study of protozoans

S Trépout, ML Sgarra, S Marco… - Molecular …, 2024 - Wiley Online Library
Since its inception in the 1930s, transmission electron microscopy (TEM) has been a
powerful method to explore the cellular structure of parasites. TEM usually requires samples …

Expansion microscopy of apicomplexan parasites

B Liffner, S Absalon - Molecular Microbiology, 2024 - Wiley Online Library
Apicomplexan parasites comprise significant pathogens of humans, livestock and wildlife,
but also represent a diverse group of eukaryotes with interesting and unique cell biology …

Correlative light and electron microscopy in parasite research

C Loussert, CL Forestier, BM Humbel - Methods in cell biology, 2012 - Elsevier
The interaction of a parasite and a host cell is a complex process, which involves several
steps:(1) attachment to the plasma membrane,(2) entry inside the host cell, and (3) hijacking …

Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid

E Bertiaux, AC Balestra, L Bournonville, V Louvel… - PLoS …, 2021 - journals.plos.org
Malaria is caused by unicellular Plasmodium parasites. Plasmodium relies on diverse
microtubule cytoskeletal structures for its reproduction, multiplication, and dissemination …