Seasonal and pandemic influenza virus infections not only pose a serious threat to human
health but also cause tremendous economic losses and social burdens. However, due to the …

Introduction: Influenza antiviral high-throughput screens have been extensive, and yet no
approved influenza antivirals have been identified through high-throughput screening. This …

Introduction: The emergence of drug-resistant influenza virus strains highlights the need for
new antiviral therapeutics to combat future pandemic outbreaks as well as continuing …

Infection with influenza A virus is still a global concern since it causes significant mortality,
morbidity and economic loss. New burst pandemics and rapid emergence of drug-resistance …

Influenza is a century-old disease that continues to baffle humans by its frequently changing
nature, seasonal epidemics, and occasional pandemics. Approximately 9% of the world's …

Drug discovery for influenza antivirals Priorities for combating pandemic influenza include
rapid detection and identification, the quick administration of available drugs to treat the …

The influenza virus causes one of the most prevalent and lethal infectious viral diseases of
the respiratory system; the disease progression varies from acute self-limiting mild fever to …

Since new and dangerous influenza virus strains, such as H5N1 “avian flu” and more
recently the swine-origin H1N1 “swine flu”, are constantly evolving, the need for effective anti …

Drugs and chemotherapeutics have helped to manage devastating impacts of infectious
diseases since the concept of 'magic bullet'. The World Health Organization estimates about …

Influenza is an acute respiratory disease caused by influenza viruses. It has the
characteristics of fast transmission and strong infectivity, and it does great harm to human …