Mechanisms of diabetic foot ulceration: a review

H Deng, B Li, Q Shen, C Zhang, L Kuang… - Journal of …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFUs) are associated with complex pathogenic factors and are
considered a serious complication of diabetes. The potential mechanisms underlying DFUs …

Genetic and molecular basis of diabetic foot ulcers: clinical review

S Jhamb, VN Vangaveti, UH Malabu - Journal of Tissue Viability, 2016 - Elsevier
Abstract Diabetic Foot Ulcers (DFUs) are major complications associated with diabetes and
often correlate with peripheral neuropathy, trauma and peripheral vascular disease. It is …

Mechanisms involved in the development and healing of diabetic foot ulceration

T Dinh, F Tecilazich, A Kafanas, J Doupis… - Diabetes, 2012 - Am Diabetes Assoc
We examined the role of vascular function and inflammation in the development and failure
to heal diabetic foot ulcers (DFUs). We followed 104 diabetic patients for a period of …

Altered molecular mechanisms of diabetic foot ulcers

R Blakytny, EB Jude - The international journal of lower …, 2009 - journals.sagepub.com
The continuously increasing worldwide prevalence of diabetes will be accompanied by a
greater incidence of diabetic foot ulcer, a complication in which many of the morphological …

Dysfunctional wound healing in diabetic foot ulcers: new crossroads

FM Davis, A Kimball, A Boniakowski… - Current diabetes reports, 2018 - Springer
Abstract Purpose of Review Diabetic foot ulcerations (DFU) affect 25% of patients with
diabetes mellitus during their lifetime and constitute a major health problem as they are often …

Pathogenesis and treatment of impaired wound healing in diabetes mellitus: new insights

D Baltzis, I Eleftheriadou, A Veves - Advances in therapy, 2014 - Springer
Diabetic foot ulcers (DFUs) are one of the most common and serious complications of
diabetes mellitus, as wound healing is impaired in the diabetic foot. Wound healing is a …

Genetic and epigenetic events in diabetic wound healing

H Rafehi, A El‐Osta… - International wound …, 2011 - Wiley Online Library
The prevalence of the chronic metabolic disorder, diabetes mellitus, is expected to increase
in the coming years and worldwide pandemic levels are predicted. Inevitably, this will be …

[HTML][HTML] The pathophysiology of diabetic foot: a narrative review

J Kim - Journal of Yeungnam Medical Science, 2023 - ncbi.nlm.nih.gov
An aging population and changes in dietary habits have increased the incidence of
diabetes, resulting in complications such as diabetic foot ulcers (DFUs). DFUs can lead to …

[HTML][HTML] Diabetic foot ulcer: A comprehensive review of pathophysiology and management modalities

JM Raja, MA Maturana, S Kayali… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Diabetic foot ulcer (DFU) is a debilitating and severe manifestation of uncontrolled and
prolonged diabetes that presents as ulceration, usually located on the plantar aspect of the …

Integrated skin transcriptomics and serum multiplex assays reveal novel mechanisms of wound healing in diabetic foot ulcers

G Theocharidis, D Baltzis, M Roustit, A Tellechea… - Diabetes, 2020 - Am Diabetes Assoc
Nonhealing diabetic foot ulcers (DFUs) are characterized by low-grade chronic
inflammation, both locally and systemically. We prospectively followed a group of patients …