Inflammatory bowel diseases (IBDs), primarily ulcerative colitis and Crohn's disease, are
inflammatory disorders caused by multiple factors. Research on IBD has often used the …

Background Dextran sodium sulfate (DSS) is used to induce murine colitis. Although the
exact mechanism by which DSS administration causes disease is unknown, evidence …

Colitis can occur from viral or bacterial infections, ischemic insult, or autoimmune disorders;
most notably Ulcerative Colitis and the colonic variant of Crohn's Disease-Crohn's Colitis …

To investigate the pathogenic mechanism of ulcerative colitis, a dextran sulfate sodium
(DSS)-induced acute colitis model was examined by serum metabolomic analysis. Higher …

Background Dextran sulfate sodium (DSS) replicates ulcerative colitis (UC)-like colitis in
murine models. However, the microbial characteristics of DSS-triggered colitis require …

Considering high prevalence of non-alcoholic fatty liver diseases (NAFLD) in patients with
inflammatory bowel disease (IBD), this study aimed to elucidate molecular mechanisms for …

Inflammatory bowel disease (IBD) encompasses a range of intestinal pathologies, the most
common of which are ulcerative colitis (UC) and Crohn's Disease (CD). Both UC and CD …

Exposure to dextran sulfate sodium (DSS) induces acute colitis, which is normally resolved
after DSS removal. To study chronicity, mice are typically subjected to three to five cycles of …

Targeted and sensitive drug release at the colitis site is critical for the effective therapy of
ulcerative colitis and reduction of side effects from the drug. Herein, we used 3, 3 …

The challenge for the treatment of inflammatory bowel disease (IBD) is the delivery of the
drug to the site of inflammation. Because nanoparticles have the ability to accumulate in …