The γ-aminobutyric acid (GABA) ergic system is the primary inhibitory neurotransmission
system in the mammalian brain. Its dysregulation has been shown in multiple brain …

Despite their possible causative role, targeting amyloidosis, tau phosphorylation,
acetylcholine esterase, glutamate, oxidative stress and mitochondrial metabolism have not …

Alzheimer's disease (AD) is the most common form of dementia in the elderly. Research
focused on identifying compounds that restore cognition and memory in AD patients is a …

Glutamatergic and cholinergic dysfunction are well‐attested features of Alzheimer's disease
(AD), progressing with other pathological indices of the disorder and exacerbating neuronal …

Alzheimer's disease (AD) is the commonest neurodegenerative disease with slow
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the vertebrate brain.
In the past, there has been a major research drive focused on the dysfunction of the …

Conclusions: Our findings demonstrated that the GABAergic system suffers significant
remodeling in the brains of AD patients, yet it is to be determined if this is as a consequence …

Alzheimer's disease (AD) is characterized pathologically by the deposition of β-amyloid
peptides (Aβ) and the accumulation of neurofibrillary tangles (NFTs) composed of hyper …

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter, playing a central role
in the regulation of cortical excitability and the maintenance of the excitatory/inhibitory (E/I) …

Glutamatergic neurotransmission system dysregulation may play an important role in the
pathophysiology of Alzheimer's disease (AD). However, reported results on glutamatergic …