In our ageing global population, the cognitive decline associated with dementia and
neurodegenerative diseases represents a major healthcare problem. To date, there are no …

Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

Cumulative evidence has indicated that there is an important role for adult hippocampal
neurogenesis in cognitive function. With the increasing prevalence of cognitive decline …

Physical exercise can convey a protective effect against cognitive decline in ageing and
Alzheimer's disease. While the long-term health-promoting and protective effects of exercise …

Although exercise has long been equated with better physical health, there is now extensive
research showing that it has substantial benefits for the brain as well. From an Alzheimer's …

Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

Given the aging populations in many countries throughout the world, there is an increasing
interest in lifestyle factors and interventions that will enhance the cognitive vitality of older …

Accumulating evidence from animal and human research indicate that adult hippocampal
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …

Alzheimer disease (AD) is the most common type of dementia in individuals over 65 years of
age. The neuropathological hallmarks of the condition are Tau neurofibrillary tangles and …

Alzheimer's disease (AD) afflicts more than 5.4 million Americans and ranks as the most
common type of dementia (Thies and Bleiler, 2011), yet effective pharmacological …