Metagenomic and metabolomic analyses unveil dysbiosis of gut microbiota in chronic heart failure patients

X Cui, L Ye, J Li, L Jin, W Wang, S Li, M Bao, S Wu… - Scientific reports, 2018 - nature.com
Previous studies suggested a possible gut microbiota dysbiosis in chronic heart failure
(CHF). However, direct evidence was lacking. In this study, we investigated the composition …

Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure

T Kamo, H Akazawa, W Suda, A Saga-Kamo… - PloS one, 2017 - journals.plos.org
Emerging evidence has suggested a potential impact of gut microbiota on the
pathophysiology of heart failure (HF). However, it is still unknown whether HF is associated …

Alterations of the gut microbiota in patients with severe chronic heart failure

W Sun, D Du, T Fu, Y Han, P Li, H Ju - Frontiers in microbiology, 2022 - frontiersin.org
Chronic heart failure (CHF) is the final outcome of almost all forms of cardiovascular
diseases, remaining the main cause of mortality worldwide. Accumulating evidence is …

Current understanding of gut microbiota alterations and related therapeutic intervention strategies in heart failure

X Chen, HY Li, XM Hu, Y Zhang… - Chinese medical journal, 2019 - mednexus.org
Objective: The purpose of this review is to stress the complicated interactions between the
microbiota and the development of heart failure. Moreover, the feasibility of modulating …

The correlation between gut microbiota and serum metabolomic in elderly patients with chronic heart failure

Z Wang, Z Cai, MW Ferrari, Y Liu, C Li… - Mediators of …, 2021 - Wiley Online Library
Objective. Chronic heart failure (CHF) refers to a state of persistent heart failure that can be
stable, deteriorated, or decompensated. The mechanism and pathogenesis of myocardial …

Heart failure is associated with depletion of core intestinal microbiota

M Luedde, T Winkler, FA Heinsen… - ESC Heart …, 2017 - Wiley Online Library
Aims In spite of current medical treatment approaches, mortality of chronic heart failure (HF)
remains high and novel treatment modalities are thus urgently needed. A recent theory …

Gut microbiome and plasma microbiome-related metabolites in patients with decompensated and compensated heart failure

T Hayashi, T Yamashita, H Watanabe, K Kami… - Circulation …, 2018 - jstage.jst.go.jp
Background: Gut microbiome composition or circulating microbiome-related metabolites in
patients with heart failure (HF) have not been investigated at different time points (ie, in the …

The implication of the gut microbiome in heart failure

VV Lupu, A Adam Raileanu, CM Mihai, ID Morariu… - Cells, 2023 - mdpi.com
Heart failure is a worldwide health problem with important consequences for the overall
wellbeing of affected individuals as well as for the healthcare system. Over recent decades …

Low fibre intake is associated with gut microbiota alterations in chronic heart failure

CCK Mayerhofer, M Kummen, K Holm… - ESC Heart …, 2020 - Wiley Online Library
Aims Recent reports have suggested that patients with heart failure (HF) have an altered gut
microbiota composition; however, associations with diet remain largely uninvestigated. We …

Changes of gut microbiome composition and metabolites associated with hypertensive heart failure rats

L Li, S Zhong, S Hu, B Cheng, H Qiu, Z Hu - BMC microbiology, 2021 - Springer
Background The potential role of the gut microbiome (GM) in heart failure (HF) had recently
been revealed. However, the underlying mechanisms of the GM and fecal metabolome in …