[HTML][HTML] Analysis of High-Risk Neuroblastoma Transcriptome Reveals Gene Co-Expression Signatures and Functional Features

ML Martínez-Pacheco, E Hernández-Lemus, C Mejía - Biology, 2023 - mdpi.com
Simple Summary Neuroblastoma is a solid cancerous tumor that forms in the nerve cells of
children, most commonly in the adrenal glands, which are located on top of both kidneys …

Global genomic and proteomic analysis identifies biological pathways related to high-risk neuroblastoma

QR Chen, YK Song, LR Yu, JS Wei… - Journal of proteome …, 2010 - ACS Publications
Neuroblastoma (NB) is a heterogeneous pediatric tumor. To better understand the biological
pathways involved in the development of high-risk neuroblastoma, we performed parallel …

Clinically relevant biomarker discovery in high-risk recurrent neuroblastoma

P Utnes, C Løkke, T Flægstad, C Einvik - Cancer informatics, 2019 - journals.sagepub.com
Neuroblastoma is a pediatric cancer of the developing sympathetic nervous system. High-
risk neuroblastoma patients typically undergo an initial remission in response to treatment …

[HTML][HTML] Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication

M Wolf, M Korja, R Karhu, H Edgren, S Kilpinen… - BMC cancer, 2010 - Springer
Background Neuroblastoma has successfully served as a model system for the identification
of neuroectoderm-derived oncogenes. However, in spite of various efforts, only a few …

[HTML][HTML] Integration of molecular features with clinical information for predicting outcomes for neuroblastoma patients

Y Han, X Ye, C Wang, Y Liu, S Zhang, W Feng… - Biology Direct, 2019 - Springer
Background Neuroblastoma is one of the most common types of pediatric cancer. In current
neuroblastoma prognosis, patients can be stratified into high-and low-risk groups. Generally …

[HTML][HTML] Signature literature review reveals AHCY, DPYSL3, and NME1 as the most recurrent prognostic genes for neuroblastoma

D Chicco, T Sanavia, G Jurman - BioData Mining, 2023 - Springer
Neuroblastoma is a childhood neurological tumor which affects hundreds of thousands of
children worldwide, and information about its prognosis can be pivotal for patients, their …

[HTML][HTML] Deep analysis of neuroblastoma core regulatory circuitries using online databases and integrated bioinformatics shows their pan-cancer roles as prognostic …

L Jahangiri, P Pucci, T Ishola, J Pereira… - Discover Oncology, 2021 - Springer
Aim Neuroblastoma is a heterogeneous childhood cancer derived from the neural crest. The
dual cell identities of neuroblastoma include Mesenchymal (MES) and Adrenergic (ADRN) …

Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number

Q Wang, S Diskin, E Rappaport, E Attiyeh, Y Mosse… - Cancer research, 2006 - AACR
Neuroblastoma is remarkable for its clinical heterogeneity and is characterized by genomic
alterations that are strongly correlated with tumor behavior. The specific genes that influence …

[HTML][HTML] Coexpression network analysis identifies transcriptional modules associated with genomic alterations in neuroblastoma

L Yang, Y Li, Z Wei, X Chang - … et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Neuroblastoma is a highly complex and heterogeneous cancer in children. Acquired
genomic alterations including MYCN amplification, 1p deletion and 11q deletion are …

Identification of key genes associated with risk and prognosis of neuroblastoma

J Zhang, Y Han, D Yan, D Zhou, X Yuan… - Journal of Molecular …, 2022 - Springer
Neuroblastoma is a childhood malignancy with high morbidity and mortality. We identified
key biomarkers associated with neuroblastoma risk and prognosis. The gene modules most …