Nanoparticle-based drug delivery system offers a promising platform for combination cancer
therapy. However, the inefficient drug release in cells reduces the therapeutic efficacy of …

The use of single chemotherapeutic drug has shown some limitations in anti-tumor
treatment, such as development of drug resistance, high toxicity and limited regime of …

Codelivery is a promising strategy to overcome the limitations of single chemotherapeutic
agents in cancer treatment. Despite progress, codelivery of two or more different functional …

Disulfide-containing nanoparticles are promising vehicles for anticancer drug delivery.
However, the preparation of disulfide-containing nanoparticles usually relies on complex …

Background It is of great significance to develop intelligent co-delivery systems for cancer
chemotherapy with improved therapeutic efficacy and few side-effects. Materials and …

The preparation of polymer therapeutics capable of controlled release of multiple
chemotherapeutic drugs has remained a tough problem in synergistic combination cancer …

Owing to their dendritic architectural features, branched copolymers have been investigated
as drug delivery systems. In this paper, an enzyme-and pH-sensitive branched poly [N-(2 …

Polymeric nanoparticles have shown great promise as attractive vehicles for drug delivery.
In this study, we designed, prepared and characterized biodegradable amphiphilic triblock …

In this study, folate-functionalized hybrid polymeric nanoparticles (NPs) were prepared as
carriers of low water solubility paclitaxel for tumor targeting, which were composed of …

Co-delivery of nucleic acids and chemotherapeutics has a potential to efficaciously treat
human diseases via their synergetic effects. Activable therapeutic tools at the nanoscale are …