[HTML][HTML] Biomimetic manganese-based theranostic nanoplatform for cancer multimodal imaging and twofold immunotherapy

Y Zhao, Y Pan, K Zou, Z Lan, G Cheng, Q Mai, H Cui… - Bioactive Materials, 2023 - Elsevier
The limited clinical response and serious side effect have been challenging in cancer
immunotherapy resulting from immunosuppressive tumor microenvironment (TME) and …

Manganese-based multifunctional nanoplatform for dual-modal imaging and synergistic therapy of breast cancer

C Zhu, Q Ma, L Gong, S Di, J Gong, Y Wang, S Xiao… - Acta Biomaterialia, 2022 - Elsevier
Manganese has recently been exploited for cancer immunotherapy, fenton-like reaction-
mediated chemo-dynamic therapy, and magnetic resonance imaging. The integration of …

NIR-II-responsive AuNRs@ SiO 2–RB@ MnO 2 nanotheranostic for multimodal imaging-guided CDT/PTT synergistic cancer therapy

C Wen, X Guo, C Gao, Z Zhu, N Meng… - Journal of Materials …, 2022 - pubs.rsc.org
Specific tumor-responsive capabilities and efficient synergistic therapeutic performance are
the keys to effective tumor treatment. Herein, AuNRs@ SiO2–RB@ MnO2 was developed as …

Manganese-enriched photonic/catalytic nanomedicine augments synergistic anti-TNBC photothermal/nanocatalytic/immuno-therapy via activating cGAS-STING …

Y Zheng, J Chen, XR Song, MQ Chang, W Feng… - Biomaterials, 2023 - Elsevier
As the clinical efficacy of immunotherapy for triple-negative breast cancer (TNBC) remains
limited, exploring new immunotherapy approaches is still indispensable. Mn 2+ has been …

Dual-targeted multifunctional nanoparticles for magnetic resonance imaging guided cancer diagnosis and therapy

X Nan, X Zhang, Y Liu, M Zhou, X Chen… - ACS applied materials …, 2017 - ACS Publications
Hybrid nanostructures with combined functionalities can be rationally designed to achieve
synergistic effects for efficient cancer treatment. Herein, a multifunctional nanoplatform is …

Multifunctional Calcium–Manganese Nanomodulator Provides Antitumor Treatment and Improved Immunotherapy via Reprogramming of the Tumor Microenvironment

G Luo, X Li, J Lin, G Ge, J Fang, W Song, GG Xiao… - ACS …, 2023 - ACS Publications
Ions play a vital role in regulating various biological processes, including metabolic and
immune homeostasis, which involves tumorigenesis and therapy. Thus, the perturbation of …

Magnetic-responsive and targeted cancer nanotheranostics by PA/MR bimodal imaging-guided photothermally triggered immunotherapy

Y Guo, Y Ran, Z Wang, J Cheng, Y Cao, C Yang, F Liu… - Biomaterials, 2019 - Elsevier
While theranostic nanoparticle (TNP)-based photothermal therapy (PTT) exhibits prominent
promise for cancer therapy, metastatic cancers remain one of the main obstacles of effective …

Manganese‐based tumor immunotherapy

K Zhang, C Qi, K Cai - Advanced Materials, 2023 - Wiley Online Library
As an essential micronutrient, manganese (Mn) participates in various physiological
processes and plays important roles in host immune system, hematopoiesis, endocrine …

Tumor-microenvironment-induced all-in-one nanoplatform for multimodal imaging-guided chemical and photothermal therapy of cancer

X Lin, Y Fang, Z Tao, X Gao, T Wang… - … Applied Materials & …, 2019 - ACS Publications
Precisely locating tumor site based on tumor-microenvironment-induced (TMI) multimodal
imaging is especially interesting for accurate and efficient cancer therapy. In the present …

A versatile metal–organic nanoplatform in combination with CXCR4 antagonist and PD-L1 inhibitor for multimodal synergistic cancer therapy and MRI-guided tumor …

D Liu, H He, F Kong, Y Cao, F Zang, M Ma, N Gu… - Nano Today, 2022 - Elsevier
Currently, multimodal synergistic nanoplatform emerges as an important cancer therapy
paradigm, however, multimodal synergistic theranostic nanoplatform remains to be …