Myelination of axons in the nervous system of vertebrates enables fast, saltatory impulse
propagation, one of the best-understood concepts in neurophysiology. However, it took a …

Myelination of axons provides the structural basis for rapid saltatory impulse propagation
along vertebrate fiber tracts, a well-established neurophysiological concept. However …

Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

The evolutionary success of the vertebrate nervous system is largely due to a unique
structural feature–the myelin sheath, a fatty envelope that surrounds the axons of neurons …

Building a functional nervous system requires the coordinated actions of many glial cells. In
the vertebrate central nervous system (CNS), oligodendrocytes myelinate neuronal axons to …

In addition to their role in providing myelin for rapid impulse propagation, the glia that
ensheath long axons are required for the maintenance of normal axon transport and long …

The study of structural and functional plasticity in the central nervous system (CNS) to date
has focused primarily on that of neurons and synapses. However, more recent studies …

Myelinated nerve fibers have evolved to enable fast and efficient transduction of electrical
signals in the nervous system. To act as an electric insulator, the myelin sheath is formed as …

Highlights•The leading edge of myelin membrane winds around the axon while spreading
laterally.•Actin filament disassembly promotes axon wrapping by myelin …

Studies of activity-driven nervous system plasticity have primarily focused on the gray matter.
However, MRI-based imaging studies have shown that white matter, primarily composed of …