Harnessing the n+1 dimensions of single-cell omics data for the prediction and prevention of
human diseases | Seminars in Immunopathology Skip to main content SpringerLink Account …

The advancement of science and technology has successfully elucidated the distinct nature
of cells, paving the way for single-cell omics. Since cells are the functional units of the …

Single-cell transcriptomics enables the definition of diverse human immune cell types across
multiple tissues and disease contexts. Further deeper biological understanding requires …

Single-cell omics technologies have revolutionized molecular profiling by providing high-
resolution insights into cellular heterogeneity and complexity. Traditional bulk omics …

To date, genome-wide association studies (GWASs) have successfully identified thousands
of associations between genetic polymorphisms and human traits. However, the pathways …

Personalized medicine represents one of the major clinical outcomes of omics applications.
Genomics and post-DNA omics allow an unprecedented characterization of the molecular …

Multi‐omics studies promise the improved characterization of biological processes across
molecular layers. However, methods for the unsupervised integration of the resulting …

The eukaryotic cell surface G protein-coupled receptors (GPCRs) interact with a wide
spectrum of ligands. The intracellular transmission of the extracellular signal is mediated by …

The tumor microenvironment (TME) is an ecosystem that contains various cell types,
including cancer cells, immune cells, stromal cells, and many others. In the TME, cancer …

This study describes the 'integrative personal omics profile'(iPOP) of a healthy person—that
of Mike Snyder, an author on the paper—which was generated by combining a whole …