The primate prefrontal cortex (PFC) subserves our highest order cognitive operations, and
yet is tremendously dependent on a precise neurochemical environment for proper …

Cortico-limbic circuits provide a substrate for adaptive behavioral and emotional responses.
However, dysfunction of these circuits can result in maladaptive responses that are …

Connections of the primate prefrontal cortex are associated with action. Within the lateral
prefrontal cortex, there are preferential targets of projections from visual, auditory, and …

The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …

The cognitive functions of the prefrontal cortex (PFC), which include use of working memory
to guide behavioral responses and the contents of attentional focus, the inhibition of …

Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

The prefrontal cortex (PFC) utilizes working memory to guide behavior and to release the
organism from dependence on environmental cues and is commonly disrupted in …

Dysfunction of the prefrontal cortex (PFC) is a central feature of many psychiatric disorders,
such as attention deficit hyperactivity disorder (ADHD), posttraumatic stress disorder (PTSD) …

This review addresses functional interactions between the primate prefrontal cortex (PFC)
and the amygdala, with emphasis on their contributions to behavior and cognition. The …

The primary symptoms of attention deficit/hyperactivity disorder (ADHD) include poor
impulse control and impaired regulation of attention. Research has shown that the prefrontal …