Adhesion of pathogenic organisms to host tissues is the prerequisite for the initiation of the
majority of infectious diseases. In many systems, it is mediated by lectins present on the …

The majority of infectious diseases are initiated by adhesion of pathogenic organisms to the
tissues of the host. In many cases, this adhesion is mediated by lectins present on the …

For a long time, carbohydrates were believed to serve solely as a source of energy and as
structural elements, and to lack biological activity. They were therefore considered as dull …

Adherence of bacteria via their surface lectins to host epithelial cells is considered an
important initial event in bacterial pathogenesis. Mannose-specific (type 1) fimbriae are …

Bacterial adherence to animal cell surfaces is of interest because of its relation to
pathogenicity and the insight it provides into determinants of intercellularrecognition. The …

The majority of infectious diseases are initiated by the adhesion of pathogenic organisms to
the tissues of the host. In many cases this adhesion is mediated by lectins present on the …

Numerous bacterial strains produce surface lectins, commonly in the form of fimbriae that
are filamentous assemblies of protein subunits. Among the best characterized of these are …

Adhesion and colonization are prerequisites for the establishment of bacterial pathogenesis.
The prevention of adhesion is an attractive target for the development of new therapies in …

The sugar specificity of Escherichia coli 346 and of the type-1 fimbriae isolated from this
organism has been studied by quantitative inhibition of the agglutination of mannan …

Lectins, non-enzymic proteins that bind mono-and oligosaccharides reversibly and with high
specificity, occur widely in nature. They come in a variety of sizes and shapes, but can be …