Circulating tumor cells dynamics in pancreatic adenocarcinoma correlate with disease status: results of the prospective CLUSTER study

G Gemenetzis, VP Groot, J Yu, D Ding… - Annals of …, 2018 - journals.lww.com
Objectives: Previous retrospective studies demonstrated that circulating tumor cells (CTCs)
subtypes correlate with overall survival in patients with pancreatic ductal adenocarcinoma …

Circulating tumor cell phenotype predicts recurrence and survival in pancreatic adenocarcinoma

KE Poruk, V Valero III, T Saunders, AL Blackford… - Annals of …, 2016 - journals.lww.com
Objective: We assessed circulating tumor cells (CTCs) with epithelial and mesenchymal
phenotypes as a potential prognostic biomarker for patients with pancreatic …

Circulating tumour cells as a biomarker for diagnosis and staging in pancreatic cancer

JS Ankeny, CM Court, S Hou, Q Li, M Song… - British journal of …, 2016 - nature.com
Background: Current diagnosis and staging of pancreatic ductal adenocarcinoma (PDAC)
has important limitations and better biomarkers are needed to guide initial therapy. We …

Circulating tumor cells predict occult metastatic disease and prognosis in pancreatic cancer

CM Court, JS Ankeny, S Sho, P Winograd… - Annals of surgical …, 2018 - Springer
Background Occult metastatic tumors, below imaging thresholds, are a limitation of staging
systems that rely on cross-sectional imaging alone and are a cause of the routine …

Improved risk stratification by circulating tumor cell counts in pancreatic cancer

KE Effenberger, C Schroeder, A Hanssen, S Wolter… - Clinical Cancer …, 2018 - AACR
Purpose: Pancreatic cancer is one of the most devastating diseases with a 5-year survival
rate of 3% to 5%. Here, we investigated whether circulating tumor cells (CTC) may predict …

[HTML][HTML] Circulating tumor cells in locally advanced pancreatic adenocarcinoma: the ancillary CirCe 07 study to the LAP 07 trial

FC Bidard, F Huguet, C Louvet, L Mineur, O Bouché… - Annals of oncology, 2013 - Elsevier
Background Pancreatic carcinoma is one of the leading causes of cancer-related mortality.
At the time of diagnosis, 30% of patients present with a locally advanced pancreatic …

Circulating tumor cells expressing markers of tumor-initiating cells predict poor survival and cancer recurrence in patients with pancreatic ductal adenocarcinoma

KE Poruk, AL Blackford, MJ Weiss, JL Cameron… - Clinical cancer …, 2017 - AACR
Abstract Purpose: Circulating tumor cells (CTCs) have been identified in the blood of
patients with pancreatic adenocarcinoma (PDAC), but little is known about the exact …

Circulating tumor cells in pancreatic cancer: current perspectives

V Martini, S Timme-Bronsert, S Fichtner-Feigl… - Cancers, 2019 - mdpi.com
Pancreatic cancer is the fourth leading cause of cancer-related death in the USA and
Europe; early symptoms and screenings are lacking, and it is usually diagnosed late with a …

Circulating tumor cells in pancreatic cancer patients: methods of detection and clinical implications

K Tjensvoll, O Nordgård… - International journal of …, 2014 - Wiley Online Library
The poor prognosis of pancreatic cancer patients is associated with the frequent and early
dissemination of the disease, as well as late detection due to unspecific and late symptoms …

[HTML][HTML] Circulating tumor cells in peripheral blood of pancreatic cancer patients and their prognostic role: a systematic review and meta-analysis

Y Wang, X Yu, D Hartmann, J Zhou - HPB, 2020 - Elsevier
Background It has been shown that circulating tumor cells in peripheral blood can be used
to predict survival in patients with breast, prostate and other epithelial tumors. In the present …