Neuroinflammation plays an important role in amyotrophic lateral sclerosis (ALS)
pathogenesis. However, it is difficult to evaluate inflammation of the central nervous system …

Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disease
affecting predominantly motor neurons in the spinal cord and motor cortex …

Exosomes contain many proteins associated with neurodegenerative diseases. To identify
new candidate biomarkers and proteins associated with amyotrophic lateral sclerosis (ALS) …

Background Non-cell autonomous toxicity is one of the potential mechanisms implicated in
the etiopathogenesis of amyotrophic lateral sclerosis (ALS). However, the exact role of glial …

Neuroinflammation is a common pathological feature of amyotrophic lateral sclerosis (ALS).
Although scientific evidence to date does not allow defining neuroinflammation as an ALS …

Background. Astrocytes can be involved in motor neuron toxicity in amyotrophic lateral
sclerosis (ALS) induced by noncell autonomous effects, and inflammatory cytokines may …

Multiple sclerosis (MS) is a putative autoimmune disease of the central nervous system
(CNS) in which autoreactive immune cells recognizing myelin antigens lead to …

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder
affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous …

Astrocytes are the most abundant glial cell type in the central nervous system (CNS) and are
known to fulfill critical homeostatic functions. Dysfunction of activated astrocytes is also …

Amyotrophic lateral sclerosis (ALS) is described as a fatal and rapidly progressive
neurodegenerative disorder caused by the degeneration of upper motor neurons in the …