[HTML][HTML] Increased interleukin-6 levels in the astrocyte-derived exosomes of sporadic amyotrophic lateral sclerosis patients
Y Chen, K Xia, L Chen, D Fan - Frontiers in Neuroscience, 2019 - frontiersin.org
Neuroinflammation plays an important role in amyotrophic lateral sclerosis (ALS)
pathogenesis. However, it is difficult to evaluate inflammation of the central nervous system …
pathogenesis. However, it is difficult to evaluate inflammation of the central nervous system …
Impaired activation of ALS monocytes by exosomes
L Zondler, MS Feiler, A Freischmidt… - Immunology and cell …, 2017 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disease
affecting predominantly motor neurons in the spinal cord and motor cortex …
affecting predominantly motor neurons in the spinal cord and motor cortex …
Proteomic analysis of exosome-enriched fractions derived from cerebrospinal fluid of amyotrophic lateral sclerosis patients
N Hayashi, H Doi, Y Kurata, H Kagawa, Y Atobe… - Neuroscience …, 2020 - Elsevier
Exosomes contain many proteins associated with neurodegenerative diseases. To identify
new candidate biomarkers and proteins associated with amyotrophic lateral sclerosis (ALS) …
new candidate biomarkers and proteins associated with amyotrophic lateral sclerosis (ALS) …
[HTML][HTML] Astroglia acquires a toxic neuroinflammatory role in response to the cerebrospinal fluid from amyotrophic lateral sclerosis patients
Background Non-cell autonomous toxicity is one of the potential mechanisms implicated in
the etiopathogenesis of amyotrophic lateral sclerosis (ALS). However, the exact role of glial …
the etiopathogenesis of amyotrophic lateral sclerosis (ALS). However, the exact role of glial …
[HTML][HTML] Looking to the Future of the Role of Macrophages and Extracellular Vesicles in Neuroinflammation in ALS
E Carata, M Muci, S Di Giulio, S Mariano… - International journal of …, 2023 - mdpi.com
Neuroinflammation is a common pathological feature of amyotrophic lateral sclerosis (ALS).
Although scientific evidence to date does not allow defining neuroinflammation as an ALS …
Although scientific evidence to date does not allow defining neuroinflammation as an ALS …
Autophagy‐Mediated Inflammatory Cytokine Secretion in Sporadic ALS Patient iPSC‐Derived Astrocytes
BaofengFeng, AE Amponsah, R Guo… - Oxidative Medicine …, 2022 - Wiley Online Library
Background. Astrocytes can be involved in motor neuron toxicity in amyotrophic lateral
sclerosis (ALS) induced by noncell autonomous effects, and inflammatory cytokines may …
sclerosis (ALS) induced by noncell autonomous effects, and inflammatory cytokines may …
The role of exosomes in CNS inflammation and their involvement in multiple sclerosis
I Selmaj, MP Mycko, CS Raine, KW Selmaj - Journal of neuroimmunology, 2017 - Elsevier
Multiple sclerosis (MS) is a putative autoimmune disease of the central nervous system
(CNS) in which autoreactive immune cells recognizing myelin antigens lead to …
(CNS) in which autoreactive immune cells recognizing myelin antigens lead to …
[HTML][HTML] Exosomes from NSC-34 cells transfected with hSOD1-G93A are enriched in miR-124 and drive alterations in microglia phenotype
S Pinto, C Cunha, M Barbosa, AR Vaz… - Frontiers in …, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder
affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous …
affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous …
[HTML][HTML] A refined bead-free method to identify astrocytic exosomes in primary glial cultures and blood plasma
CM Willis, A Ménoret, ER Jellison, AM Nicaise… - Frontiers in …, 2017 - frontiersin.org
Astrocytes are the most abundant glial cell type in the central nervous system (CNS) and are
known to fulfill critical homeostatic functions. Dysfunction of activated astrocytes is also …
known to fulfill critical homeostatic functions. Dysfunction of activated astrocytes is also …
[HTML][HTML] Extracellular vesicles as potential biomarkers in amyotrophic lateral sclerosis
M Barbo, M Ravnik-Glavač - Genes, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is described as a fatal and rapidly progressive
neurodegenerative disorder caused by the degeneration of upper motor neurons in the …
neurodegenerative disorder caused by the degeneration of upper motor neurons in the …