Mechanism of action of gestagens

BM Landgren - International Journal of Gynecology & Obstetrics, 1990 - Elsevier
In the mid-1950s it was shown that ovulation can be inhibited by oral administration of
progesterone or of synthetic progestogens such as norethynodrel. The idea that …

[PDF][PDF] Low level progestogens

E Diczfalusy, BM Landgren - Professor, Department of Obstetrics and …, 1983 - pdf.usaid.gov
Inconceptual terms the history of low level pregestogens as fertil ity regulating agents may
be traced to the end of the last century, when Beard and Preinant observed that no ovulation …

[引用][C] Development of the oral contraceptives

MC Chang - American Journal of Obstetrics and Gynecology, 1978 - Elsevier
DLIRINCTHESECONDWORLDWAR, lwasworkingin the laboratory of Sir John Hammond
and Dr. Arthur Walton at Cambridge University on methods of preservation of mammalian …

[引用][C] The role of progestogens in the hormonal control of fertility

HW Rudel, J Martinez-Manautou, M Maqueo-Topete - Fertility and sterility, 1965 - Elsevier
MATERIALS AND METHODS Women whose pregnancy history proved them to be fertile
were selected for study. In certain instances confirmation of their ovulatory status was sought …

Endocrinological effects of oral contraceptives

A Klopper - Clinics in Endocrinology and Metabolism, 1973 - Elsevier
The chief endocrinological effect of oral contraceptives is exercised on the feedback
mechanism of the gonadal steroids to the hypothalamus. Apparently the receptor …

Progesterone and ovulation

S Zalanyi - European Journal of Obstetrics & Gynecology and …, 2001 - Elsevier
The role of progesterone (P) in the mechanism of ovulation is controversial at best. The
contraceptive application of P was established in rodents in 1936 and with orally absorbed …

Long-term contraceptive effect of injectable progestogens: inhibition and reestabilishment of fertility

J Zanartu - International journal of fertility, 1968 - pubmed.ncbi.nlm.nih.gov
PIP: The antifertility effect of long-acting injectable progestogens was evaluated in 2,000
young, fertile women observed during 34,800 woman-months. Depo-medroxyprogesterone …

[引用][C] The role of estrogens and progesterone in ovulation.

RH Dutt - 1953 - cabidigitallibrary.org
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Depression of the progesterone levels in women treated with synthetic gestagens after ovulation

EDB Johansson - European Journal of Endocrinology, 1971 - academic.oup.com
Abstract Norethisterone1), norgestrel, chlormadinone acetate or medroxyprogesterone
acetate was given orally from the third day after ovulation or later for various numbers of …

Ovulation inhibition with different doses of Levonorgestrel* and other progestogens: clinical and experimental investigations

J Spona, WHF Schneider, C Bieglmayer… - Acta Obstetricia et …, 1979 - Wiley Online Library
Model systems were evaluated, which can be used to determine biological activities of
progestogens at various cell levels of the anterior pituitary gland. in addition, various …