Since its inception, liquid chromatography-mass spectrometry (LC-MS) has been
continuously improved upon in many aspects, including instrument capabilities, sensitivity …

LC-MS-based quantitative proteomics has become increasingly applied to a wide range of
biological applications due to growing capabilities for broad proteome coverage and good …

With the development of new quantitative strategies and powerful bioinformatics tools to
cope with the analysis of the large amounts of data generated in proteomics experiments …

Mass spectrometry instrumentation has continued to develop rapidly in the last two decades,
enabled in part by advances in microelectronic hardware controllers and computerized …

In recent years, the technology and methods widely available for mass spectrometry (MS)-
based proteomics have increased in power and potential, allowing the study of protein-level …

Liquid chromatography/mass spectrometry (LC/MS) has become a powerful technology in
proteomics studies in drug discovery, including target protein characterization and discovery …

Liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based proteomics is a
powerful technique for profiling proteomes of cells, tissues, and body fluids. Typical bottom …

Mass spectrometry (MS)-based proteomics has become an indispensable tool with broad
applications in systems biology and biomedical research. With recent advances in liquid …

With advances in ionization methods and instrumentation, liquid chromatography (LC)/mass
spectrometry (MS) has become a powerful technology for protein characterization. This …

Mass spectrometers now have sufficient sensitivity and acquisition rates to allow analysis of
complex proteomic samples on a chromatographic timescale. In this chapter the different …