Systemic consequences of pulmonary hypertension and right-sided heart failure

S Rosenkranz, LS Howard, M Gomberg-Maitland… - Circulation, 2020 - Am Heart Assoc
Pulmonary hypertension (PH) is a feature of a variety of diseases and continues to harbor
high morbidity and mortality. The main consequence of PH is right-sided heart failure which …

Pulmonary hypertension in heart failure: pathophysiology, pathobiology, and emerging clinical perspectives

M Guazzi, R Naeije - Journal of the American College of Cardiology, 2017 - jacc.org
Pulmonary hypertension is a common hemodynamic complication of heart failure. Interest in
left-sided pulmonary hypertension has increased remarkably in recent years because its …

Pulmonary hypertension with left-sided heart disease

M Guazzi, R Arena - Nature Reviews Cardiology, 2010 - nature.com
Pulmonary hypertension (PH) with left-sided heart disease is defined, according to the latest
Venice classification, as a Group 2 PH, which includes left-sided ventricular or atrial disease …

The pathophysiology of pulmonary hypertension in left heart disease

S Breitling, K Ravindran… - … of Physiology-Lung …, 2015 - journals.physiology.org
Pulmonary hypertension (PH) is characterized by elevated pulmonary arterial pressure
leading to right-sided heart failure and can arise from a wide range of etiologies. The most …

Pulmonary hypertension due to left heart disease

M Guazzi, BA Borlaug - Circulation, 2012 - Am Heart Assoc
Pulmonary hypertension (PH) due to left heart disease, classified as group 2 according to
the Dana Point 2008 classification, is believed to be the most common cause of PH and is …

Pulmonary hypertension and right heart dysfunction in chronic lung disease

A Zangiabadi, CG De Pasquale… - BioMed research …, 2014 - Wiley Online Library
Group 3 pulmonary hypertension (PH) is a common complication of chronic lung disease
(CLD), including chronic obstructive pulmonary disease (COPD), interstitial lung disease …

Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology

A Vonk-Noordegraaf, F Haddad, KM Chin… - Journal of the American …, 2013 - jacc.org
Survival in patients with pulmonary arterial hypertension (PAH) is closely related to right
ventricular (RV) function. Although pulmonary load is an important determinant of RV …

Pulmonary heart disease: The heart-lung interaction and its impact on patient phenotypes

PR Forfia, A Vaidya, SE Wiegers - Pulmonary circulation, 2013 - journals.sagepub.com
Pulmonary heart disease (PHD) refers to altered structure or function of the right ventricle
occurring in association with abnormal respiratory function. Although nearly always …

Pulmonary hypertension in left heart disease

M Guazzi, N Galie - European Respiratory Review, 2012 - Eur Respiratory Soc
Pulmonary hypertension (PH) is a frequent complication of left heart disease arising from a
wide range of cardiac disorders. In the clinical classification, PH associated with left heart …

The latest in animal models of pulmonary hypertension and right ventricular failure

O Boucherat, V Agrawal, A Lawrie, S Bonnet - Circulation research, 2022 - Am Heart Assoc
Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …