Safety and efficacy of P2Y12 inhibitor monotherapy in patients undergoing percutaneous coronary interventions

M Galli, D Capodanno, F Andreotti, F Crea… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: Antiplatelet therapy represents a key strategy for the prevention of thrombotic
complications in patients with both acute and chronic coronary syndromes, particularly those …

P2Y12 inhibitor monotherapy in patients undergoing percutaneous coronary intervention

D Capodanno, U Baber, DL Bhatt, JP Collet… - Nature Reviews …, 2022 - nature.com
For 20 years, dual antiplatelet therapy (DAPT), consisting of the combination of aspirin and a
platelet P2Y12 receptor inhibitor, has been the gold standard of antithrombotic …

Long-term effects of P2Y12 inhibitor monotherapy after percutaneous coronary intervention: 3-year follow-up of the SMART-CHOICE randomized clinical trial

KH Choi, YH Park, YB Song, TK Park, JM Lee… - JAMA …, 2022 - jamanetwork.com
Importance Although P2Y12 inhibitor monotherapy after a minimum period of dual
antiplatelet therapy (DAPT) is a well-known way to reduce the risk of bleeding after …

P2Y12 Inhibitor Monotherapy after Percutaneous Coronary Intervention

X Zhou, DJ Angiolillo, L Ortega-Paz - Journal of Cardiovascular …, 2022 - mdpi.com
In patients with acute and chronic coronary artery disease undergoing percutaneous
coronary intervention (PCI), dual antiplatelet therapy (DAPT) has been the cornerstone of …

[HTML][HTML] Antiplatelet therapy in PCI

A Fanaroff, S Rao - Interventional cardiology clinics, 2016 - ncbi.nlm.nih.gov
Platelets play a key role in mediating stent thrombosis, the major cause of ischemic events in
the immediate period following percutaneous coronary intervention (PCI). For this reason …

P2Y12 Inhibitor monotherapy versus conventional dual antiplatelet therapy in patients with acute coronary syndrome after percutaneous coronary intervention: a meta …

WH Feng, YC Chang, YH Lin, HL Chen, CY Chen… - Pharmaceuticals, 2023 - mdpi.com
P2Y12 inhibitor monotherapy is a feasible alternative treatment for patients after
percutaneous coronary intervention (PCI) in the modern era. Clinical trials have shown that it …

P2Y12-inhibitor monotherapy after coronary stenting: are all P2Y12-inhibitors equal?

NMR van der Sangen, IT Küçük… - Expert review of …, 2022 - Taylor & Francis
Introduction P2Y12-inhibitor monotherapy following 1–3 months of dual antiplatelet therapy
(DAPT) reduces (major) bleeding without an apparent increase in ischemic events and has …

P2Y12 inhibitors monotherapy in patients undergoing complex vs non-complex percutaneous coronary intervention: a meta-analysis of randomized trials

A Oliva, DS Castiello, A Franzone, G Condorelli… - American Heart …, 2023 - Elsevier
Abstract Background Monotherapy with P2Y12 inhibitors (P2Y12i) is emerging as alternative
strategy to dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) …

P2Y12 inhibitor monotherapy after coronary stenting according to type of P2Y12 inhibitor

J Kim, WJ Jang, WS Lee, KH Choi, JM Lee, TK Park… - Heart, 2021 - heart.bmj.com
Objective To compare P2Y12 inhibitor monotherapy after 3-month dual antiplatelet therapy
(DAPT) with 12-month DAPT according to the type of P2Y12 inhibitor in patients undergoing …

Platelet P2Y12 inhibitor monotherapy after percutaneous coronary intervention: an emerging option for antiplatelet therapy de-escalation

FWA Verheugt, K Huber, P Clemmensen… - Thrombosis and …, 2023 - thieme-connect.com
Antiplatelet therapy is considered essential for secondary prevention of ischemic heart
disease. After percutaneous coronary intervention (PCI), temporary dual antiplatelet therapy …