Efflux Pump Activity and Mutations Driving Multidrug Resistance in Acinetobacter baumannii at a Tertiary Hospital in Pretoria, South Africa

ND Nogbou, GM Nkawane, K Ntshane… - International Journal …, 2021 - Wiley Online Library
Acinetobacter baumannii (A. baumannii) has developed several resistance mechanisms.
The bacteria have been reported as origin of multiple outbreaks. This study aims to …

[HTML][HTML] Investigating multi-drug resistant Acinetobacter baumannii isolates at a tertiary hospital in Pretoria, South Africa

ND Nogbou, DT Phofa, M Nchabeleng… - Indian Journal of Medical …, 2021 - Elsevier
Purpose Antimicrobial resistance is now globally recognised amongst the greatest threat to
human health. Acinetobacter baumannii's'(A. baumannii) clinical significance has been …

Functional analysis of multidrug efflux pumps genes of Acinetobacter baumannii strains.

H Goudarzi, M Doraghi, H Dabiri, Z Ghalavand - 2013 - cabidigitallibrary.org
Background: Efflux systems are components of the bacterial membrane that play a role in
homeostasis of the cell and extrusion of toxic compounds. Efflux pumps of the resistance …

Detection of efflux pump genes conferring multidrug resistance in clinical isolates of Acinetobacter Baumannii in Tehran province

H Beikmohammadi, S Viesy, R Kaviani… - Reviews and Research …, 2022 - journals.lww.com
Objective: Acinetobacter baumannii is among the most common bacterial agents causing
nosocomial infections in the world. In recent years, the antibiotic resistance of A. baumannii …

Insertion sequence disruption of adeR and ciprofloxacin resistance caused by efflux pumps and gyrA and parC mutations in Acinetobacter baumannii

BS Lopes, SGB Amyes - International journal of antimicrobial agents, 2013 - Elsevier
Acinetobacter baumannii is a pathogenic bacterium responsible for a wide range of
infections in immunocompromised patients. This study examined the role of insertional …

Contribution of different mechanisms to aminoglycoside resistance in clinical isolates of Acinetobacter baumannii

NM Saleh, SI Saad, M El-Sayed, GS El-Sayyad… - Microbial …, 2023 - Elsevier
The antibiotics overuse for infection treatment was the sparkle in the spreading of multi-drug
resistance Acinetobacter baumannii in hospitals. In our study, we evaluated the contribution …

[PDF][PDF] AdeABC efflux pump genes in multidrug resistant Acinetobacter baumannii isolates

KA Jassim, KK Ghaima… - Avicenna Journal of …, 2016 - ajcmi.umsha.ac.ir
Objectives: Acinetobacter baumannii is an opportunistic nosocomial pathogen and a cause
of severe infections in hospitalized patients, owing to its ability to acquire drug resistance by …

Multi-drug resistance profiles and the genetic features of Acinetobacter baumannii isolates from Bolivia

BS Lopes, L Gallego Andrés, SGB Amyes - 2013 - addi.ehu.es
Introduction: Acinetobacter baumannii is opportunistic in debilitated hospitalised patients.
Because information from some South American countries was previously lacking, this study …

Prevalence of eight resistance-nodulation-division efflux pump genes in epidemiologically characterized Acinetobacter baumannii of worldwide origin

J Nowak, H Seifert, PG Higgins - Journal of medical …, 2015 - microbiologyresearch.org
The increasing emergence of multidrug-resistant Acinetobacter baumannii constitutes a
worldwide threat in hospital settings. Efflux-mediated resistance, particularly the resistance …

Antimicrobial Resistance Mechanisms and Genetic Diversity of Multidrug-Resistant Acinetobacter baumannii Isolated from a Teaching Hospital in Malaysia

S Biglari, A Hanafiah, S Mohd Puzi, R Ramli… - Microbial Drug …, 2017 - liebertpub.com
Multidrug-resistant (MDR) Acinetobacter baumannii has increasingly emerged as an
important nosocomial pathogen. The aim of this study was to determine the resistance …