VDAC, a channel in the outer mitochondrial membrane

M Colombini, E Blachly-Dyson, M Forte - Ion channels, 1996 - Springer
Proteins that form aqueous channels in membranes generate conduction pathways with a
variety of shapes and sizes. Perhaps the largest channel-forming protein is the 2-MDa …

[HTML][HTML] VDAC isoforms in mammals

A Messina, S Reina, F Guarino, V De Pinto - Biochimica et Biophysica Acta …, 2012 - Elsevier
VDACs (Voltage Dependent Anion selective Channels) are a family of pore-forming proteins
discovered in the mitochondrial outer membrane. In the animal kingdom, mammals show a …

VDAC: the channel at the interface between mitochondria and the cytosol

M Colombini - Molecular and cellular biochemistry, 2004 - Springer
The mitochondrial outer membrane is not just a barrier but a site of regulation of
mitochondrial function. The VDAC family of proteins are the major pathways for metabolite …

Mouse VDAC isoforms expressed in yeast: channel properties and their roles in mitochondrial outer membrane permeability

X Xu, W Decker, MJ Sampson, WJ Craigen… - The Journal of …, 1999 - Springer
The channel-forming protein called VDAC forms the major pathway in the mitochondrial
outer membrane and controls metabolite flux across that membrane. The different VDAC …

Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms

E Blachly-Dyson, A Baldini, M Litt, ERB McCabe… - Genomics, 1994 - Elsevier
The voltage-dependent anion channel of the mitochondrial outer membrane (VDAC) is a
small, abundant pore-forming protein found in the outer membranes of all eukaryotic …

[HTML][HTML] Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.

E Blachly-Dyson, EB Zambronicz, WH Yu… - Journal of Biological …, 1993 - Elsevier
The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane is a
small abundant protein found in all eukaryotic kingdoms which forms a voltage-gated pore …

[HTML][HTML] VDAC structure, selectivity, and dynamics

M Colombini - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2012 - Elsevier
VDAC channels exist in the mitochondrial outer membrane of all eukaryotic organisms. Of
the different isoforms present in one organism, it seems that one of these is the canonical …

The mitochondrial outer membrane channel, VDAC, is modulated by a soluble protein

MJ Holden, M Colombini - FEBS letters, 1988 - Wiley Online Library
The mitochondrial outer membrane channel, VDAC, serves as the primary permeability
pathway for metabolite flux between cytoplasmic and mitochondrial compartments. VDAC …

VDAC regulation: role of cytosolic proteins and mitochondrial lipids

TK Rostovtseva, SM Bezrukov - Journal of bioenergetics and …, 2008 - Springer
It was recently asserted that the voltage-dependent anion channel (VDAC) serves as a
global regulator, or governor, of mitochondrial function (Lemasters and Holmuhamedov …

[HTML][HTML] VDAC2-specific cellular functions and the underlying structure

S Naghdi, G Hajnóczky - Biochimica Et Biophysica Acta (BBA)-Molecular …, 2016 - Elsevier
Abstract Voltage Dependent Anion-selective Channel 2 (VDAC2) contributes to oxidative
metabolism by sharing a role in solute transport across the outer mitochondrial membrane …