Heart failure causes significant morbidity and mortality worldwide. The understanding of
heart failure pathomechanisms and options for treatment remain incomplete. Zebrafish has …

Heart disease is the leading cause of death worldwide. Despite decades of research, most
heart pathologies have limited treatments, and often the only curative approach is heart …

Heart failure is a complex pathophysiological syndrome of pumping functional failure that
results from injury, infection or toxin-induced damage on the myocardium, as well as genetic …

Cardiovascular disease (CVD) is one of the leading causes of death worldwide. The most
significant risk factors associated with the development of heart diseases include genetic …

Understanding the molecular and cellular mechanisms underlying normal development and
pathological conditions is an important step toward preventing and developing effective …

The zebrafish has been rapidly adopted as a model for cardiac development and disease.
The transparency of the embryo, its limited requirement for active oxygen delivery, and ease …

Over the last decade, the zebrafish has entered the field of cardiovascular research as a
new model organism. This is largely due to a number of highly successful small-and large …

The heart is the first functional organ to form during vertebrate development. Congenital
heart defects are the most common type of human birth defect, many originating as …

Cardiomyopathies are a highly heterogeneous group of heart muscle disorders. More than
100 causative genes have been linked to various cardiomyopathies, which explain about …

Animal models of cardiovascular disease are key players in the translational medicine
pipeline used to define the conserved genetic and molecular basis of disease. Congenital …