Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …
Antimicrobial peptides under clinical investigation
HB Koo, J Seo - Peptide Science, 2019 - Wiley Online Library
Overuse of conventional antibiotics as well as the slow pace of new antibiotic drug
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …
[HTML][HTML] Discovery, optimization, and clinical application of natural antimicrobial peptides
Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …
diverse molecules are produced as the first line of defense against pathogens such as …
Antimicrobial peptides: therapeutic potentials
SJ Kang, SJ Park, T Mishig-Ochir… - Expert review of anti …, 2014 - Taylor & Francis
The increasing appearance of multidrug-resistant pathogens has created an urgent need for
suitable alternatives to current antibiotics. Antimicrobial peptides (AMPs), which act as …
suitable alternatives to current antibiotics. Antimicrobial peptides (AMPs), which act as …
[HTML][HTML] Development and challenges of antimicrobial peptides for therapeutic applications
More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …
Advances on chemically modified antimicrobial peptides for generating peptide antibiotics
SB Rezende, KGN Oshiro, NGO Júnior… - Chemical …, 2021 - pubs.rsc.org
Antimicrobial peptides (AMPs) are pinpointed as promising molecules against antibiotic-
resistant bacterial infections. Nevertheless, there is a discrepancy between the AMP …
resistant bacterial infections. Nevertheless, there is a discrepancy between the AMP …
Membrane‐active small molecules: designs inspired by antimicrobial peptides
Infectious diseases continue to be one of the major contributors to human morbidity. The
rapid rate at which pathogenic microorganisms have developed resistance against frontline …
rapid rate at which pathogenic microorganisms have developed resistance against frontline …
Antimicrobial peptides: recent insights on biotechnological interventions and future perspectives
R Sinha, P Shukla - Protein and peptide letters, 2019 - ingentaconnect.com
With the unprecedented rise of drug-resistant pathogens, particularly antibiotic-resistant
bacteria, and no new antibiotics in the pipeline over the last three decades, the issue of …
bacteria, and no new antibiotics in the pipeline over the last three decades, the issue of …
[HTML][HTML] Antimicrobial peptides and proteins: from nature's reservoir to the laboratory and beyond
Rapid rise of antimicrobial resistance against conventional antimicrobials, resurgence of
multidrug resistant microbes and the slowdown in the development of new classes of …
multidrug resistant microbes and the slowdown in the development of new classes of …
Designing and optimizing new antimicrobial peptides: all targets are not the same
A Barreto-Santamaría, ME Patarroyo… - Critical Reviews in …, 2019 - Taylor & Francis
Because the resistance of microorganisms to the available antibiotics is a growing
healthcare problem worldwide, the search for new antimicrobial peptides (AMPs) that …
healthcare problem worldwide, the search for new antimicrobial peptides (AMPs) that …
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