Background Opioid dependence is associated with substantial health and social burdens,
and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for …

The aim of this review was to update and summarize the scientific knowledge on the long
term outcomes of the different pharmacological treatment options for opioid dependence …

Background Opiate dependence is becoming increasingly prevalent, with associated
increases in the spread of infectious disease (eg HIV, hepatitis B and C) and overdose …

Background Buprenorphine maintenance treatment has been evaluated in randomised
controlled trials against placebo medication, and separately as an alternative to methadone …

Aims To assess the efficacy of buprenorphine compared with methadone maintenance
therapy for opioid dependence in a large sample using a flexible dosing regime and the …

Background Opioids are psychoactive analgesic drugs prescribed for pain relief and
palliative care. Due to their addictive potential, effort and vigilance in controlling …

Objectives To review current evidence on buprenorphine–naloxone (bup/nx) for the
treatment of opioid-use disorders, with a focus on strategies for clinical management and …

Background The average length of buprenorphine treatment for opioid use disorder is less
than 6 months. Objective We conducted a systematic review to determine what factors were …

Introduction: Management of patients with opioid use disorder (OUD) commonly includes
opioid agonist therapy (OAT) as a part of an integrated treatment plan. These interventions …

Objective Buprenorphine maintenance treatment (BMT) and methadone maintenance
treatment (MMT) are pharmacological treatment programs for individuals with opioid use …