[HTML][HTML] Bisphenol A attenuates the therapeutic effect of the selective G protein-coupled estrogen receptor agonist G-1 on allergic rhinitis inflammation in mice

Y Wang, Z Cao, H Zhao, Z Gu - Ecotoxicology and Environmental Safety, 2022 - Elsevier
Abstract Background Bisphenol A (BPA) is found in many plastics widely used in everyday
life and affects the immune system. Previous studies found that the selective G protein …

The environmental hormone nonylphenol interferes with the therapeutic effects of G protein-coupled estrogen receptor specific agonist G-1 on murine allergic rhinitis

Y Wang, Z Gu, L Hao - International Immunopharmacology, 2020 - Elsevier
The G protein-coupled estrogen receptor (GPER) specific agonist G-1 has therapeutic
effects in patients with allergic diseases, but any role for G-1 as a therapy for inflammation …

Bisphenol A exacerbates allergic inflammation in an ovalbumin‐induced mouse model of allergic rhinitis

Y Wang, Z Cao, H Zhao, Y Ren… - Journal of Immunology …, 2020 - Wiley Online Library
Purpose. Bisphenol A (BPA) is found in many plastic products and is thus a common
environmental endocrine disruptor. Plastic‐related health problems, including allergic …

[HTML][HTML] G-protein-coupled estrogen receptor agonist suppresses airway inflammation in a mouse model of asthma through IL-10

M Itoga, Y Konno, Y Moritoki, Y Saito, W Ito, M Tamaki… - PLoS …, 2015 - journals.plos.org
Estrogen influences the disease severity and sexual dimorphism in asthma, which is caused
by complex mechanisms. Besides classical nuclear estrogen receptors (ERαβ), G-protein …

[HTML][HTML] Oral exposure to low dose bisphenol A aggravates allergic airway inflammation in mice

R Yanagisawa, E Koike, TT Win-Shwe, H Takano - Toxicology Reports, 2019 - Elsevier
Bisphenol A (BPA) is widely used in many consumer products and has adverse effects on
human health including allergic diseases. We investigated the effects of low dose BPA …

[HTML][HTML] Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma

M Itoga, Y Ishioka, T Makiguchi, H Tanaka, K Taima… - Immunology …, 2024 - Elsevier
Background and Aim G protein-coupled estrogen receptor (GPER) is an estrogen receptor
located on the plasma membrane. We previously reported that the administration of G-1, a …

Oral administration of bisphenol A directly exacerbates allergic airway inflammation but not allergic skin inflammation in mice

R Tajiki-Nishino, E Makino, Y Watanabe… - Toxicological …, 2018 - academic.oup.com
Bisphenol A (BPA) is used in various areas of daily life as a major component of plastic
products. However, it is also known as a strong endocrine disruptor that affects the human …

[HTML][HTML] Effects of oral exposure to low-dose Bisphenol S on allergic asthma in mice

R Yanagisawa, E Koike, TT Win-Shwe… - International Journal of …, 2022 - mdpi.com
Bisphenol S (BPS) is increasingly being used as an alternative for bisphenol A; however, its
health effects remain unclear. We investigated the effects of oral exposure to low-dose BPS …

Nonylphenol can aggravate allergic rhinitis in a murine model by regulating important Th cell subtypes and their associated cytokines

Y Wang, Z Gu, Z Cao, L Hao - International Immunopharmacology, 2019 - Elsevier
Nonylphenol (NP) is a widely distributed, toxic endocrine-disrupting chemical exhibiting
estrogenic activity. However, its effect on allergic rhinitis (AR) remains unclear. In this study …

[HTML][HTML] Endocrine disruptor bisphenol A (BPA) triggers systemic para-inflammation and is sufficient to induce airway allergic sensitization in mice

LF Loffredo, ME Coden, S Berdnikovs - Nutrients, 2020 - mdpi.com
Allergic airway diseases are accompanied by increased permeability and an inflammatory
state of epithelial barriers, which are thought to be susceptible to allergen sensitization …