[HTML][HTML] Antimicrobial and Anti-Biofilm Peptide Octominin for Controlling Multidrug-Resistant Acinetobacter baumannii

EHTT Jayathilaka, DC Rajapaksha… - International Journal of …, 2021 - mdpi.com
Acinetobacter baumannii is a serious nosocomial pathogen with multiple drug resistance
(MDR), the control of which has become challenging due to the currently used antibiotics …

[HTML][HTML] The Antimicrobial Peptide Octopromycin Suppresses Biofilm Formation and Quorum Sensing in Acinetobacter baumannii

DC Rajapaksha, SL Edirisinghe, C Nikapitiya, I Whang… - Antibiotics, 2023 - mdpi.com
Acinetobacter baumannii is an opportunistic bacterial pathogen that causes severe
infections in immunocompromised individuals. A. baumannii forms biofilm and produces …

[HTML][HTML] Octominin: A Novel Synthetic Anticandidal Peptide Derived from Defense Protein of Octopus minor

C Nikapitiya, SHS Dananjaya, H Chandrarathna… - Marine drugs, 2020 - mdpi.com
The rapid emergence of multidrug-resistant pathogens makes an urgent need for
discovering novel antimicrobial agents as alternatives to conventional antibiotics. Towards …

[HTML][HTML] Antimicrobial peptide octominin-encapsulated chitosan nanoparticles enhanced antifungal and antibacterial activities

EHTT Jayathilaka, C Nikapitiya, M De Zoysa… - International Journal of …, 2022 - mdpi.com
Antimicrobial peptides (AMPs) have become a key solution for controlling multi-drug-
resistant (MDR) pathogens, and the nanoencapsulation of AMPs has been used as a …

[HTML][HTML] Antifungal Efficacy of Antimicrobial Peptide Octominin II against Candida albicans

JNC Jayasinghe, I Whang, M De Zoysa - International Journal of …, 2023 - mdpi.com
Most clinically isolated Candida albicans strains are drug-resistant, emphasizing the urgent
need to discover alternative therapies. In this study, the previously characterized Octominin …

[HTML][HTML] Antimicrobial Activity of Selected Antimicrobial Peptides Against Planktonic Culture and Biofilm of Acinetobacter baumannii

M Jaśkiewicz, D Neubauer, K Kazor… - Probiotics and …, 2019 - Springer
Acinetobacter baumannii is one of the most challenging pathogens, on account of its
predisposition to develop resistance leading to severe, difficult-to-treat infections. As these …

[HTML][HTML] In Vitro Evaluation of Antimicrobial Peptide Tridecaptin M in Combination with Other Antibiotics against Multidrug Resistant Acinetobacter baumannii

M Jangra, V Raka, H Nandanwar - Molecules, 2020 - mdpi.com
The rapid emergence of antimicrobial resistance in Acinetobacter baumannii coupled with
the dried pipeline of novel treatments has driven the search for new therapeutic modalities …

[HTML][HTML] OmpA Binding Mediates the Effect of Antimicrobial Peptide LL-37 on Acinetobacter baumannii

MF Lin, PW Tsai, JY Chen, YY Lin, CY Lan - PLoS One, 2015 - journals.plos.org
Multidrug-resistant Acinetobacter baumannii has recently emerged as an important
pathogen in nosocomial infection; thus, effective antimicrobial regimens are urgently …

Antimicrobial peptides as a promising treatment option against Acinetobacter baumannii infections

A Neshani, H Sedighian, SA Mirhosseini… - Microbial …, 2020 - Elsevier
Background With the increasing rate of antibiotic resistance in Acinetobacter, the World
Health Organization introduced the carbapenem-resistant isolates in the priority pathogens …

Synergistic effects and antibiofilm properties of chimeric peptides against multidrug-resistant Acinetobacter baumannii strains

R Gopal, YG Kim, JH Lee, SK Lee… - Antimicrobial agents …, 2014 - Am Soc Microbiol
The increasing prevalence of drug-resistant pathogens highlights the need to identify novel
antibiotics. Here we investigated the efficacies of four new antimicrobial peptides (AMPs) for …