Upgrading prevascularization in tissue engineering: a review of strategies for promoting highly organized microvascular network formation

D Sharma, D Ross, G Wang, W Jia, SJ Kirkpatrick… - Acta Biomaterialia, 2019 - Elsevier
Functional and perfusable vascular network formation is critical to ensure the long-term
survival and functionality of engineered tissues after their transplantation. Although several …

Prevascularization in tissue engineering: current concepts and future directions

MW Laschke, MD Menger - Biotechnology advances, 2016 - Elsevier
The survival of engineered tissue constructs during the initial phase after their implantation
depends on the rapid development of an adequate vascularization. This, in turn, is a major …

Microvascular tissue engineering—A review

J Vajda, M Milojević, U Maver, B Vihar - Biomedicines, 2021 - mdpi.com
Tissue engineering and regenerative medicine have come a long way in recent decades,
but the lack of functioning vasculature is still a major obstacle preventing the development of …

Engineering the multiscale complexity of vascular networks

C O'Connor, E Brady, Y Zheng, E Moore… - Nature Reviews …, 2022 - nature.com
The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

The pivotal role of vascularization in tissue engineering

FA Auger, L Gibot, D Lacroix - Annual review of biomedical …, 2013 - annualreviews.org
Vascularization is one of the great challenges that tissue engineering faces in order to
achieve sizeable tissue and organ substitutes that contain living cells. There are instances …

From arteries to capillaries: approaches to engineering human vasculature

S Fleischer, DN Tavakol… - Advanced functional …, 2020 - Wiley Online Library
From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …

Engineering new microvascular networks on‐chip: ingredients, assembly, and best practices

JJ Tronolone, A Jain - Advanced functional materials, 2021 - Wiley Online Library
Tissue engineered grafts show great potential as regenerative implants for diseased or
injured tissues within the human body. However, these grafts suffer from poor nutrient …

Angiogenesis in tissue engineering: as nature intended?

V Mastrullo, W Cathery, E Velliou… - … in bioengineering and …, 2020 - frontiersin.org
Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Engineering blood vessels and vascularized tissues: technology trends and potential clinical applications

P Chandra, A Atala - Clinical Science, 2019 - portlandpress.com
Vascular tissue engineering has the potential to make a significant impact on the treatment
of a wide variety of medical conditions, including providing in vitro generated vascularized …

Microfabricated biomaterials for engineering 3D tissues

P Zorlutuna, N Annabi, G Camci‐Unal… - Advanced …, 2012 - Wiley Online Library
Mimicking natural tissue structure is crucial for engineered tissues with intended
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …