COVID-19 convalescent plasma and clinical trials: understanding conflicting outcomes
D Focosi, M Franchini, L Pirofski… - Clinical microbiology …, 2022 - Am Soc Microbiol
Convalescent plasma (CP) recurs as a frontline treatment in epidemics because it is
available as soon as there are survivors. The COVID-19 pandemic represented the first …
available as soon as there are survivors. The COVID-19 pandemic represented the first …
Association of convalescent plasma treatment with clinical status in patients hospitalized with COVID-19: a meta-analysis
Importance COVID-19 convalescent plasma (CCP) is a potentially beneficial treatment for
COVID-19 that requires rigorous testing. Objective To compile individual patient data from …
COVID-19 that requires rigorous testing. Objective To compile individual patient data from …
Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients
P Millat-Martinez, A Gharbharan, A Alemany… - Nature …, 2022 - nature.com
Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed
to assess whether CP administered during the first week of symptoms reduced the disease …
to assess whether CP administered during the first week of symptoms reduced the disease …
Convalescent plasma therapy in COVID-19: Unravelling the data using the principles of antibody therapy
A Casadevall, MJ Joyner, LA Pirofski… - Expert review of …, 2023 - Taylor & Francis
Introduction When the COVID-19 pandemic struck no specific therapies were available and
many turned to COVID-19 convalescent plasma (CCP), a form of antibody therapy. The …
many turned to COVID-19 convalescent plasma (CCP), a form of antibody therapy. The …
Guidance on the use of convalescent plasma to treat immunocompromised patients with coronavirus disease 2019
Abstract Coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) is a safe and
effective treatment for COVID-19 in immunocompromised (IC) patients. IC patients have a …
effective treatment for COVID-19 in immunocompromised (IC) patients. IC patients have a …
One-year follow-up of the CAPSID randomized trial for high-dose convalescent plasma in severe COVID-19 patients
S Körper, B Grüner, D Zickler… - The Journal of …, 2022 - Am Soc Clin Investig
BACKGROUND Results of many randomized trials on COVID-19 convalescent plasma
(CCP) have been reported, but information on long-term outcome after CCP treatment is …
(CCP) have been reported, but information on long-term outcome after CCP treatment is …
A randomized controlled study of convalescent plasma for individuals hospitalized with COVID-19 pneumonia
Background Antibody-based strategies for COVID-19 have shown promise in prevention
and treatment of early disease. COVID-19 convalescent plasma (CCP) has been widely …
and treatment of early disease. COVID-19 convalescent plasma (CCP) has been widely …
Efficacy and safety of COVID-19 convalescent plasma in hospitalized patients: a randomized clinical trial
MB Ortigoza, H Yoon, KS Goldfeld… - JAMA internal …, 2022 - jamanetwork.com
Importance There is clinical equipoise for COVID-19 convalescent plasma (CCP) use in
patients hospitalized with COVID-19. Objective To determine the safety and efficacy of CCP …
patients hospitalized with COVID-19. Objective To determine the safety and efficacy of CCP …
COVID-19 convalescent plasma
As the coronavirus disease (COVID-19) pandemic led to a global health crisis, there were
limited treatment options and no prophylactic therapies for those exposed to severe acute …
limited treatment options and no prophylactic therapies for those exposed to severe acute …
Early versus deferred anti-SARS-CoV-2 convalescent plasma in patients admitted for COVID-19: A randomized phase II clinical trial
ME Balcells, L Rojas, N Le Corre… - PLoS …, 2021 - journals.plos.org
Background Convalescent plasma (CP), despite limited evidence on its efficacy, is being
widely used as a compassionate therapy for hospitalized patients with COVID-19. We aimed …
widely used as a compassionate therapy for hospitalized patients with COVID-19. We aimed …
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