Efficient synthesis, antibacterial, antifungal, antioxidant and cytotoxicity study of 2‐(2‐hydrazineyl) thiazole derivatives

VA Adole, RA More, BS Jagdale, TB Pawar… - …, 2020 - Wiley Online Library
In the present investigation, an alluring green PEG‐400 mediated one‐pot synthesis of
novel 2‐(2‐hydrazinyl) thiazole derivatives from 1, 2, 6, 7‐tetrahydro‐8H‐indeno [5, 4‐b] …

Design, synthesis and biological evaluation of new series of benzotriazole-pyrazole clubbed thiazole hybrids as bioactive heterocycles: Antibacterial, antifungal …

KB Gangurde, RA More, VA Adole… - Journal of Molecular …, 2024 - Elsevier
The need for novel heterocyclic compounds with robust biological action is a result of the
emergence of numerous pandemics and microbial resistance. To search antibacterial and …

[HTML][HTML] Design, synthesis and docking studies of new hydrazinyl-thiazole derivatives as anticancer and antimicrobial agents

AM El-Naggar, A Zidan, EB Elkaeed… - Journal of Saudi …, 2022 - Elsevier
Increase in the number of infections caused by pathogenic microbes in cancer patients has
prompted the searcher to invest in the development of agents having dual anticancer and …

A facile access and evaluation of some novel thiazole and 1, 3, 4-thiadiazole derivatives incorporating thiazole moiety as potent anticancer agents

SM Gomha, MR Abdelaziz, NA Kheder… - Chemistry Central …, 2017 - Springer
Background Many heterocyclic compounds containing thiazole or 1, 3, 4-thiadiazole ring in
their skeletons have been reported to possess various pharmacological activities especially …

Synthesis, anti-inflammatory and antimicrobial evaluation of novel 1-acetyl-3, 5-diaryl-4, 5-dihydro (1H) pyrazole derivatives bearing urea, thiourea and sulfonamide …

AP Keche, GD Hatnapure, RH Tale, AH Rodge… - Bioorganic & medicinal …, 2012 - Elsevier
A series of novel 1-acetyl-3-(3, 4-dimethoxypheny)-5-(4-(3-(arylureido/arylthioureido/
arylsulfonamido) phenyl)-4, 5-dihydropyrazole derivatives of biological interest have been …

Synthesis, X-ray crystallographic, spectroscopic and computational studies of aminothiazole derivatives

M Adeel, AAC Braga, MN Tahir, F Haq, M Khalid… - Journal of Molecular …, 2017 - Elsevier
Aminothiazole organic compounds have diverse biological applications. Herein we report
the synthesis of two aminothiazole derivatives: 4-(biphenyl-4-yl) thiazol-2-amine (1) and 4 …

Synthesis, molecular docking study, and cytotoxicity evaluation of some novel 1, 3, 4-thiadiazole as well as 1, 3-thiazole derivatives bearing a pyridine moiety

AS Abouzied, JY Al-Humaidi, AS Bazaid, H Qanash… - Molecules, 2022 - mdpi.com
Pyridine, 1, 3, 4-thiadiazole, and 1, 3-thiazole derivatives have various biological activities,
such as antimicrobial, analgesic, anticonvulsant, and antitubercular, as well as other …

Exploring of antioxidant and antibacterial properties of novel 1, 3, 4-thiadiazole derivatives: Facile synthesis, structural elucidation and DFT approach to antioxidant …

H Muğlu, M Akın, MS Çavuş, H Yakan, N Şaki… - … biology and chemistry, 2022 - Elsevier
In recent years, compounds containing thiophene and 1, 3, 4-thiadiazole skeletons have
become important cyclic compounds, especially in medicinal chemistry. In this manner, we …

Synthesis, antibacterial activity and quantum-chemical studies of novel 2-arylidenehydrazinyl-4-arylthiazole analogues

MS Alam, L Liu, YE Lee, DU Lee - Chemical and Pharmaceutical …, 2011 - jstage.jst.go.jp
A new series of 2-arylidenehydrazinyl-4-arylthiazole derivatives (2a—k) was designed and
synthesized through a rapid, simple, and efficient methodology in excellent isolated yield …

Design, synthesis, characterization, in vitro screening, molecular docking, 3D-QSAR, and ADME-Tox investigations of novel pyrazole derivatives as antimicrobial …

M Chalkha, M Akhazzane, FZ Moussaid… - New Journal of …, 2022 - pubs.rsc.org
In this work, we report the synthesis of some new pyrazole derivatives via an efficient and
practical procedure. The structures of the obtained compounds were established using …