The endogenous ligand of CB 1 cannabinoid receptors, anandamide, is also a full agonist at
vanilloid VR1 receptors for capsaicin and resiniferatoxin, thereby causing an increase in …

Some synthetic agonists of the VR1 vanilloid (capsaicin) receptor also inhibit the facilitated
transport into cells of the endogenous cannabinoid anandamide (arachidonoylethanolamide …

This study was directed at exploring the structure‐activity relationship for anandamide and
certain of its analogues at the rat VR1 receptor in transfected cells and at investigating the …

Anandamide was the first endogenous ligand of cannabinoid receptors to be discovered in
1992. Yet, this compound also efficiently activates receptors specific for capsaicin, known as …

We investigated the effect of changing the length and degree of unsaturation of the fatty acyl
chain of N-(3-methoxy-4-hydroxy)-benzyl-cis-9-octadecenoamide (olvanil), a ligand of …

The endogenous cannabinoid anandamide was identified as an agonist for the recombinant
human VR1 (hVR1) by screening a large array of bioactive substances using a FLIPR …

The endogenous cannabinoid receptor ligand, anandamide (AEA), is a full agonist of the
vanilloid receptor type 1 (VR1) for capsaicin. Here, we demonstrate that the potency and …

Anandamide: an endogenous activator of the vanilloid receptor Page 1 134 TiPS – April 2000
(Vol. 21) LETTERS Two recent articles1,2 have discussed whether the cannabinoid …

In spite of the rapid advances in our understanding of vanilloid-receptor pharmacology in the
PNS, the function of vanilloid receptors in the brain has remained elusive. Recently, the …

In human embryonic kidney cells over-expressing the human vanilloid receptor type 1
(VR1), palmitoylethanolamide (PEA, 0.5–10 μM) enhanced the effect of …