Drug repurposing for viral cancers: a paradigm of machine learning, deep learning, and virtual screening‐based approaches

F Ahmed, IS Kang, KH Kim, A Asif… - Journal of Medical …, 2023 - Wiley Online Library
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …

Artificial intelligence, machine learning, and drug repurposing in cancer

Z Tanoli, M Vähä-Koskela… - Expert opinion on drug …, 2021 - Taylor & Francis
Introduction: Drug repurposing provides a cost-effective strategy to re-use approved drugs
for new medical indications. Several machine learning (ML) and artificial intelligence (AI) …

[PDF][PDF] Drug repurposing in antiviral research: a current scenario

D Mani, A Wadhwani… - Journal of Young …, 2019 - jyoungpharm.org
Better understand the unexplored parts of the drugs you know than the drugs unidentified.
Drug repurposing is a promising, fast and cost-effective method that can overcome …

Drug repurposing—an emerging strategy in cancer therapeutics

KS Turabi, A Deshmukh, S Paul, D Swami… - Naunyn-Schmiedeberg's …, 2022 - Springer
Cancer is a complex disease affecting millions of people around the world. Despite
advances in surgical and radiation therapy, chemotherapy continues to be an important …

Drug repurposing: A strategy for discovering inhibitors against emerging viral infections

IJ dos Santos Nascimento… - Current Medicinal …, 2021 - ingentaconnect.com
Background: Viral diseases are responsible for several deaths around the world. Over the
past few years, the world has seen several outbreaks caused by viral diseases that, for a …

[HTML][HTML] Drug repurposing: re-inventing therapies for cancer without re-entering the development pipeline—a review

S Siddiqui, AJ Deshmukh, P Mudaliar… - Journal of the Egyptian …, 2022 - Springer
While majority of the current treatment approaches for cancer remain expensive and are
associated with several side effects, development of new treatment modalities takes a …

[HTML][HTML] Drug repurposing approaches to combating viral infections

J Trivedi, M Mohan, SN Byrareddy - Journal of clinical medicine, 2020 - mdpi.com
Development of novel antiviral molecules from the beginning costs an average of
350millionto 2 billion per drug, and the journey from the laboratory to the clinic takes about …

A new computational drug repurposing method using established disease–drug pair knowledge

N Saberian, A Peyvandipour, M Donato, S Ansari… - …, 2019 - academic.oup.com
Motivation Drug repurposing is a potential alternative to the classical drug discovery
pipeline. Repurposing involves finding novel indications for already approved drugs. In this …

[HTML][HTML] Machine learning applications in drug repurposing

F Yang, Q Zhang, X Ji, Y Zhang, W Li, S Peng… - Interdisciplinary Sciences …, 2022 - Springer
Abstract The coronavirus disease (COVID-19) has led to an rush to repurpose existing
drugs, although the underlying evidence base is of variable quality. Drug repurposing is a …

[HTML][HTML] SperoPredictor: an integrated machine learning and molecular docking-based drug repurposing framework with use case of COVID-19

F Ahmed, JW Lee, A Samantasinghar, YS Kim… - Frontiers in public …, 2022 - frontiersin.org
The global spread of the SARS coronavirus 2 (SARS-CoV-2), its manifestation in human
hosts as a contagious disease, and its variants have induced a pandemic resulting in the …