We described in this article the very efficient 2, 6-cis ou 2, 4, 6-cis diastereoselective
synthesis (2 or 3 steps, 62–65% global yields) from Prins-cyclization reaction as synthetic …

A novel cascade strategy has been developed for the synthesis of tetrahydrospiro [chroman-
2, 4′-pyran] derivatives by condensation of aldehydes with 2-(5-hydroxy-3 …

We described in this paper the first synthesis to the (±) cis (6-ethyl-tetrahydropyran-2-yl)
formic acid (1) using the very efficient Prins cyclization reaction as strategy to construction of …

The natural products having tetrahydropyran unit with multiple chiral centers serve as
magnificent building blocks for various active pharmaceutical ingredients (APIs).'Prins …

Following our previously reported Prins cyclization strategy, a series of novel and highly
functionalized flavonoid based THPs (Prins products) were designed, synthesized and …

Functionalized tetrahydropyran (THP) rings are important building blocks and ubiquitous
scaffolds in many natural products and active pharmaceutical ingredients (API). Among …

The construction of cis-fused heterobicyclic system involved in neuroactive natural products
such as dysiherbaine has been accomplished by employing Prins strategy using 1, 3, 5 …

A series of cis-2, 6-dialkyl-4-chloro-tetrahydropyrans were prepared by means of an iron (III)-
catalyzed process. The in vitro antiproliferative activities were examined in the human solid …

Diastereoselective Synthesis of Dihydropyrans via Prins Cyclization of Enol Ethers: Total
Asymmetric Synthesis of (+)-Civet Cat Compound | The Journal of Organic Chemistry ACS ACS …

Tetrahydropyranones are synthesized from 3-bromobut-3-en-1-ols and aldehydes in good
yields with excellent diastereoselectivity at− 35° C. The reaction involves an initial formation …