Appraisal of evidence reliability and applicability of Paxlovid as treatment for SARS‐COV‐2 infection: A systematic review

C Zhu, JY Yin, X Chen, M Liu… - Reviews in Medical …, 2023 - Wiley Online Library
This study aimed to clarify the beneficial effect and the clinical application value of Paxlovid
in the treatment of coronavirus disease‐19 (COVID‐19) through a systematic review …

Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study

J Liu, X Pan, S Zhang, M Li, K Ma, C Fan… - The Lancet Regional …, 2023 - thelancet.com
Summary Background Nirmatrelvir plus ritonavir (Paxlovid) reduced the risk of
hospitalization or death by 89% in high-risk, ambulatory adults with COVID-19. We aimed at …

Efficacy and safety of paxlovid (nirmatrelvir/ritonavir) in the treatment of COVID‐19: An updated meta‐analysis and trial sequential analysis

H Tian, C Yang, T Song, K Zhou, L Wen… - Reviews in Medical …, 2023 - Wiley Online Library
Our study is aimed to access the efficacy and safety outcomes for coronavirus disease 2019
(COVID‐19) patients treated with Paxlovid. According to inclusion and exclusion criteria …

A retrospective cohort study of Paxlovid efficacy depending on treatment time in hospitalized COVID-19 patients

Z Du, L Wang, Y Bai, Y Liu, EHY Lau, AP Galvani… - Elife, 2024 - elifesciences.org
Paxlovid, a SARS-CoV-2 antiviral, not only prevents severe illness but also curtails viral
shedding, lowering transmission risks from treated patients. By fitting a mathematical model …

Evaluation of oral small molecule drugs for the treatment of COVID-19 patients: a systematic review and network meta-analysis

Z Chen, F Tian - Annals of Medicine, 2023 - Taylor & Francis
Introduction At present, there are some randomized controlled trials (RCTs) of oral small
molecule drugs. The purpose of this study was to evaluate the efficacy and safety of oral …

Effectiveness of paxlovid in reducing severe coronavirus disease 2019 and mortality in high-risk patients

R Najjar-Debbiny, N Gronich, G Weber… - Clinical Infectious …, 2023 - academic.oup.com
Background Paxlovid was granted an Emergency Use Authorization for the treatment of mild
to moderate coronavirus disease 2019 (COVID-19), based on the interim analysis of the …

Safety and efficacy of Paxlovid against Omicron variants of coronavirus disease 2019 in elderly patients

C Weng, R Xie, G Han, Y Yuan, S Li, C Wang… - Infectious Diseases and …, 2023 - Springer
Introduction Elderly patients are the most affected and vulnerable to COVID-19 and effective
therapeutic interventions are urgently required. We clarified the safety and efficacy of …

[HTML][HTML] The feasibility, safety, and efficacy of Paxlovid treatment in SARS-CoV-2-infected children aged 6–14 years: a cohort study

G Yan, J Zhou, H Zhu, Y Chen, Y Lu… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Paxlovid is recognized as an effective medication in preventing the progression
of coronavirus disease of 2019 (COVID-19) to severe form in adults; however, its efficacy …

Efficacy and safety of Paxlovid for COVID-19: a meta-analysis

Q Zheng, P Ma, M Wang, Y Cheng, M Zhou… - Journal of …, 2023 - journalofinfection.com
We read with interest the manuscript “Sensitivity and specificity of surveillance case
definitions in detection of influenza and respiratory syncytial virus among hospitalized …

Paxlovid: A promising drug for the challenging treatment of SARS-COV-2 in the pandemic era

N Niraj, SS Mahajan, A Prakash… - Indian Journal of …, 2022 - journals.lww.com
Coronavirus infection is a pandemic threat and the most dangerous disease of the 21 st
century. Despite the rigorous exertion of world-class researchers, there is no perfect cure for …