Anthracyclin-treated tumor cells are particularly effective in eliciting an anticancer immune
response, whereas other DNA-damaging agents such as etoposide and mitomycin C do not …

The treatment of cancer by chemotherapy causes tumour cell death, mostly by apoptosis.
This tumour cell death may or may not elicit an immune response. At least in some cases …

In contrast to prior belief, tumor cell apoptosis is not necessarily silent but can be
immunogenic. By tracing how anthracyclines and γ-irradiation trigger immunogenic cell …

Some chemotherapeutic agents can elicit apoptotic cancer cell death, thereby activating an
anticancer immune response that influences therapeutic outcome. We previously reported …

The conventional treatment of cancer relies upon radiotherapy and chemotherapy. Such
treatments supposedly mediate their effects via the direct elimination of tumor cells …

Experiments performed in mice revealed that anthracyclines stimulate immunogenic cell
death that is characterized by the pre-apoptotic exposure of calreticulin (CRT) on the surface …

Calreticulin exposure increases cancer immunogenicity | Nature Biotechnology Skip to
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The exposure of calreticulin (CRT) on the surface of stressed and dying cancer cells
facilitates their uptake by dendritic cells and the subsequent presentation of tumor …

Dying tumour cells can elicit a potent anticancer immune response by exposing the
calreticulin (CRT)/ERp57 complex on the cell surface before the cells manifest any signs of …

Several pieces of experimental evidence indicate the following: 1) the most efficient
antitumor treatments (this principle applies on both chemotherapy and radiotherapy) are …