Synergistic effects of low-level stress and a Western diet on metabolic homeostasis, mood, and myocardial ischemic tolerance

EF Du Toit, WS Tai, A Cox… - American Journal …, 2020 - journals.physiology.org
How low-level psychological stress and overnutrition interact in influencing cardiometabolic
disease is unclear. Mechanistic overlaps suggest potential synergies; however, findings are …

Stress‐induced body weight loss and improvements in cardiometabolic risk factors do not translate to improved myocardial ischemic tolerance in western diet‐fed …

K Hatton‐Jones, AJ Cox, JN Peart… - Physiological …, 2022 - Wiley Online Library
Although both diet‐induced obesity and psychological stress are recognized as significant
independent contributors to cardiometabolic and behavioral disorders, our understanding of …

Opposing effects of chronic stress and weight restriction on cardiovascular, neuroendocrine and metabolic function

JN Flak, R Jankord, MB Solomon, EG Krause… - Physiology & …, 2011 - Elsevier
Chronic stress is associated with dysregulation of energy homeostasis, but the link between
the two is largely unknown. For most rodents, periods of chronic stress reduce weight gain …

[HTML][HTML] Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats

R Wan, S Camandola, MP Mattson - The Journal of nutrition, 2003 - Elsevier
Stressful events may trigger disease processes in many different organ systems, with the
cardiovascular system being particularly vulnerable. Five-mo-old male rats had ad libitum …

High-fat, low-carbohydrate diet alters myocardial oxidative stress and impairs recovery of cardiac function after ischemia and reperfusion in obese rats

J Liu, SG Lloyd - Nutrition research, 2013 - Elsevier
Obesity is associated with elevated risk of heart disease. A solid understanding of the safety
and potential adverse effects of high-fat, low-carbohydrate diet (HFLCD) similar to that used …

Calorie restriction attenuates inflammatory responses to myocardial ischemia-reperfusion injury

B Chandrasekar, JF Nelson… - American Journal of …, 2001 - journals.physiology.org
The life-prolonging effects of calorie restriction (CR) may be due to reduced damage from
cumulative oxidative stress. Our goal was to determine the long-term effects of moderate …

Impact of high-fat, low-carbohydrate diet on myocardial substrate oxidation, insulin sensitivity, and cardiac function after ischemia-reperfusion

J Liu, P Wang, SL Douglas, JM Tate… - American Journal …, 2016 - journals.physiology.org
High-fat, low-carbohydrate Diet (HFLCD) impairs the myocardial response to ischemia-
reperfusion, but the underlying mechanisms remain elusive. We sought to determine the …

Central and cardiac stress resilience consistently linked to integrated immuno‐neuroendocrine responses across stress models in male mice

TJ Helman, JP Headrick, JN Peart… - European Journal of …, 2022 - Wiley Online Library
Stress resilience, and behavioural and cardiovascular impacts of chronic stress, are
theorised to involve integrated neuro‐endocrine/inflammatory/transmitter/trophin signalling …

Time‐restricted feeding alleviates cardiac dysfunction induced by simulated microgravity via restoring cardiac FGF21 signaling

XP Wang, CY Xing, JX Zhang, JH Zhou… - The FASEB …, 2020 - Wiley Online Library
Dietary restriction has been well‐described to improve health metrics, but whether it could
benefit pathophysiological adaptation to extreme environment, for example, microgravity …

Inherited stress resiliency prevents the development of metabolic alterations in diet‐induced obese mice

M Ben‐Shachar, T Daniel, A Wollman, S Govindaraj… - …, 2023 - Wiley Online Library
Objective Chronic stress promotes obesity and metabolic comorbidities. The ability of
individuals to cope with stress may serve as an important parameter in the development of …