Free Fatty Acid-Induced Cellular Stress Response and Protective Role of Palmitoleate
PK Sahoo - 2023 - search.proquest.com
Maternal obesity has emerged as a significant health challenge in the 21 st century and has
been shown to influence the health of the fetus in utero and later in life. The prevalence of …
been shown to influence the health of the fetus in utero and later in life. The prevalence of …
Palmitate induces integrated stress response and lipoapoptosis in trophoblasts
Maternal obesity increases the risk of childhood obesity and programs the offspring to
develop metabolic syndrome later in their life. Palmitate is the predominant saturated free …
develop metabolic syndrome later in their life. Palmitate is the predominant saturated free …
Saturated Free Fatty Acids Induce Trophoblast Lipoapoptosis
SK Natarajan, T Bruett, E Muthukrishnan… - The FASEB …, 2017 - Wiley Online Library
Obesity during pregnancy increases the risk for maternal complications like gestational
diabetes, preeclampsia, and maternal inflammation. Maternal obesity also increases the risk …
diabetes, preeclampsia, and maternal inflammation. Maternal obesity also increases the risk …
Saturated free fatty acids induce placental trophoblast lipoapoptosis
Introduction Obesity during pregnancy increases the risk for maternal complications like
gestational diabetes, preeclampsia, and maternal inflammation. Maternal obesity also …
gestational diabetes, preeclampsia, and maternal inflammation. Maternal obesity also …
[PDF][PDF] Oleate attenuates palmitate-induced endoplasmic reticulum stress and apoptosis in placental trophoblasts
BN Colvin, MS Longtine, B Chen, ML Costa… - …, 2017 - repositorio.unicamp.br
Pre-pregnancy body mass index determines pregnancy outcome (Nelson et al. 2010, Flegal
et al. 2012), and more than half of pregnant women in the United States are overweight or …
et al. 2012), and more than half of pregnant women in the United States are overweight or …
Oleate protects macrophages from palmitate-induced apoptosis through the downregulation of CD36 expression
DH Kim, YM Cho, KH Lee, SW Jeong… - … and biophysical research …, 2017 - Elsevier
In obese patients, free fatty acids ectopically accumulated in non-adipose tissues cause cell
death. Saturated fatty acids are more deleterious to non-adipose cells, and supplementation …
death. Saturated fatty acids are more deleterious to non-adipose cells, and supplementation …
Preimplantation exposure of mouse embryos to palmitic acid results in fetal growth restriction followed by catch-up growth in the offspring
ES Jungheim, ED Louden, MMY Chi… - Biology of …, 2011 - academic.oup.com
Free fatty acids (FFAs) are energy substrates for many cell types, but in excess, some FFAs
can accumulate in nonadipose cells, inducing apoptosis. Also known as lipotoxicity, this …
can accumulate in nonadipose cells, inducing apoptosis. Also known as lipotoxicity, this …
Docosahexaenoic acid antagonizes the boosting effect of palmitic acid on LPS inflammatory signaling by inhibiting gene transcription and ceramide synthesis
J Jin, Z Lu, Y Li, LA Cowart, MF Lopes-Virella… - PloS one, 2018 - journals.plos.org
It is well known that saturated fatty acids (SFAs) and unsaturated fatty acid, in particular
omega-3 polyunsaturated fatty acids (n-3 PUFAs), have different effects on inflammatory …
omega-3 polyunsaturated fatty acids (n-3 PUFAs), have different effects on inflammatory …
[HTML][HTML] Palmitate activates the NF-κB transcription factor and induces IL-6 and TNFα expression in 3T3-L1 adipocytes
KM Ajuwon, ME Spurlock - The Journal of nutrition, 2005 - Elsevier
Fatty acids and their metabolites regulate gene expression and immunological pathways.
Furthermore, obese individuals frequently have increased circulating fatty acid …
Furthermore, obese individuals frequently have increased circulating fatty acid …
[HTML][HTML] Palmitic acid induces inflammatory cytokines and regulates tRNA-derived stress-induced RNAs in human trophoblasts
High levels of proinflammatory cytokines have been observed in obese pregnancies.
Obesity during pregnancy may increase the risk of various pregnancyrelated complications …
Obesity during pregnancy may increase the risk of various pregnancyrelated complications …