Shigella flexneri possesses multiple iron acquisition systems, including proteins involved in
the synthesis and uptake of siderophores and the Feo system for ferrous iron utilization. We …

Shigella spp. have transport systems for both ferric and ferrous iron. The iron can be taken
up as free iron or complexed to a variety of carriers. All Shigella species have both the Feo …

The sit-encoded iron transport system is present within pathogenicity islands in all Shigella
spp. and some pathogenic Escherichia coli strains. The islands contain numerous insertion …

Shigella species are able to grow in a variety of environments, including intracellularly in
host epithelial cells. Shigella have a number of different iron transport systems that …

Shigella flexneri possesses at least two putative high-affinity manganese acquisition
systems, SitABCD and MntH. Mutations in the genes encoding the components of both of …

Iron uptake systems which are critical for bacterial survival and which may play important
roles in bacterial virulence are often carried on mobile elements, such as plasmids and …

Shigella species can use heme as the sole source of iron. In this work, the heme utilization
locus of Shigella dysenteriae was cloned and characterized. A cosmid bank of S …

Iron limitation, a condition encountered within mammalian hosts, induces the synthesis of a
number of proteins in pathogenic Shigella species. These include several outer membrane …

Mutants of Shigella flexneri defective in aerobactin-mediated iron transport were assayed for
virulence in several model systems. A Tn5 insertion mutant was invasive in HeLa cells …

The iron uptake systems of Plesiomonas shigelloides strains were determined. Siderophore
production was not detected by chemical or biological assays, and the strains tested were …