Poststroke recovery processes include restoration or compensation of function, respectively
functions initially lost or new functions acquired after an injury. Therapeutic interventions can …

Stroke is not only a leading cause of death worldwide but also a main cause of disability. In
developing countries, its burden is increasing as a consequence of a higher life expectancy …

Ischemic stroke is the most frequent neurological disease, characterized by an age-related
incidence and chronic disability in the majority of patients. A great challenge in acute stroke …

Stroke recovery therapeutics include many classes of intervention and numerous treatment
targets. Stroke is a very heterogeneous disease. As such, stroke recovery therapeutics …

Restorative cell-based and pharmacological therapies for experimental stroke substantially
improve functional outcome. These therapies target several types of parenchymal cells …

Clinical trials for acute stroke treatments have often used composite clinical rating scales as
primary outcome measures of treatment efficacy. Recent preclinical and clinical studies …

Enhancing the Alignment of the Preclinical and Clinical Stroke Recovery Research Pipeline:
Consensus-Based Core Recommendations From the Stroke Recovery and Rehabilitation …

Approximately 700,000 people in the United States have an ischemic stroke annually.
Substantial research has tested therapies for the very early treatment of ischemic stroke but …

Novel therapeutic intervention that aims to enhance the endogenous recovery potential of
the brain during the subacute phase of stroke has produced promising results. The …

Stroke is the second leading cause of death and the preeminent cause of neurological
disability. Attempts to limit brain injury after ischemic stroke with clot-dissolving drugs have …