Chemical risk assessment relies on knowledge of hazard, the dose–response relationship,
and exposure to characterize potential risks to public health and the environment. A …

Background: Computational exposure science represents a frontier of environmental
science that is emerging and quickly evolving. Objectives: In this commentary, we define this …

A new generation of scientific tools has emerged to rapidly measure signals from cells,
tissues, and organisms following exposure to chemicals. High-visibility efforts to apply these …

Background The US Environmental Protection Agency is facing large challenges in
managing environmental chemicals with increasingly complex requirements for assessing …

The computational modeling of human exposure to environmental pollutants is one of the
primary activities of the US Environmental Protection Agency (USEPA)'s National Exposure …

Exposure science is evolving from its traditional “after the fact” and “one chemical at a time”
approach to forecasting chemical exposures rapidly enough to keep pace with the …

Scientifically sound, risk-informed evaluation of chemicals is essential to protecting public
health. Systematically leveraging information from exposure, toxicology, and epidemiology …

The emerging field of computational toxicology applies mathematical and computer models
and molecular biological and chemical approaches to explore both qualitative and …

We are at the dawn of a new era of quantitative consumer exposure and risk assessment of
chemicals driven by regulatory mandates. This remarkable development also signals the …

Background: Scientists and regulatory agencies strive to identify chemicals that may cause
harmful effects to humans and the environment; however, prioritization is challenging …