Background Primary angioedema (PA) is a complex disorder, presenting multiple hereditary
(hereditary angioedema) and acquired subtypes (acquired angioedema). Despite a very …

The evolution in the knowledge of rare genetic diseases such as hereditary angioedema
(HAE) has increased at a parallel pace with the development of new molecular tools. The …

Hereditary angioedema (HAE) is a heterogeneous genetic disease caused by a deficit in C1
inhibitor (C1-INH) and clinically characterized by sudden events of edema, swelling, and …

Background Hereditary angioedema (HAE) is a rare genetic disease. Patients with type II
HAE have normal or elevated C1-inhibitor (C1-INH) levels but C1-INH protein is …

Background Hereditary angioedema (HAE) is a rare genetic disease usually caused by
mutation in the C1 inhibitor or the coagulation Factor XII gene. However, in a series of …

Background Hereditary angioedema (HAE) is a rare and life-threatening inborn error of
immunity. HAE is mostly caused by pathogenic variations in the serine protease inhibitor …

Hereditary angioedema (HAE) is a rare, chronic, debilitating genetic disorder characterized
by recurrent, unpredictable, and potentially life-threatening episodes of swelling that …

Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is caused by mutations
affecting the SERPING1 gene. Adult patients (≥ 18 years old) diagnosed with C1-INH-HAE …

Hereditary angioedema (HAE) poses diagnostic challenges due to its episodic, non-specific
symptoms and overlapping conditions. This study focuses on the genetic basis of HAE …

Hereditary angioedema (HAE) poses a high burden of disease, being its epidemiological
and clinical data heterogeneous among countries, with no recent published studies …